SCHEMBL3190230

SCHEMBL3190230

CCOC(=O)C(C)(O)CC(=O)N(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 1/20 0.40
MGAM O43451 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
CYP4F2 P78329 3/20 0.38
CYP4A11 Q02928 3/20 0.38
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
PKM P14618 3/20 0.36
MMP8 P22894 1/20 0.36
ALDH1A1 P00352 4/20 0.36
TRPA1 O75762 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
TSHR P16473 2/20 0.35
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3280616 0.83 GAA (0.46) STING1MGAMGAASIMGAM2
SCHEMBL8207151 0.82 DGAT1 (0.34) MGAMGAASIMGAM2ALDH1A1
SCHEMBL3085616 0.81 ALDH1A1 (0.40) MGAMGAASIMGAM2CYP4F2
SCHEMBL4716166 0.80 MMP8 (0.43) STING1MGAMGAASIMGAM2
SCHEMBL6667303 0.79 HMGCR (0.46) STING1CYP4F2CYP4A11PKMMMP8
SCHEMBL2242736 0.76 CYP4F2 (0.44) STING1MGAMGAASIMGAM2
SCHEMBL12386545 0.76 CYP4F2 (0.44) STING1MGAMGAASIMGAM2
SCHEMBL12574804 0.76 STING1 (0.40) STING1MGAMGAASIMGAM2
SCHEMBL2217971 0.74 PKM (0.48) STING1MGAMGAASIMGAM2
SCHEMBL11487636 0.74 PKM (0.48) STING1MGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8383695-B2 Phenoxy resin for optical material, resin composition for optical material, resin film for optical material and optical waveguide using those HITACHI CHEMICAL COMPANY, LTD. (JP) 2013-02-26 US disclosed
US-7660503-B2 Flexible optical waveguide and optical module HITACHI CHEMICAL COMPANY, LTD. (JP) 2010-02-09 US disclosed
US-20090175585-A1 Flexible Optical Waveguide and Optical Module HITACHI CHEMICAL COMPANY, LTD. (JP) 2009-07-09 US disclosed
US-20090062421-A1 Phenoxy Resin for Optical Material, Resin Composition for Optical Material, Resin Film For Optical Material and Optical Waveguide Using Those HITACHI CHEIMICAL COMPANY LTD. (JP) 2009-03-05 US disclosed
EP-1995266-A1 PHENOXY RESIN FOR OPTICAL MATERIAL, RESIN COMPOSITION FOR OPTICAL MATERIAL, RESIN FILM FOR OPTICAL MATERIAL, AND OPTICAL WAVEGUIDE USING THOSE Hitachi Chemical Co., Ltd. (JP) 2008-11-26 EP disclosed
EP-1983360-A1 FLEXIBLE OPTICAL WAVEGUIDE AND OPTICAL MODULE Hitachi Chemical Co., Ltd. (JP) 2008-10-22 EP disclosed