SCHEMBL3192467

SCHEMBL3192467

O=C1OC(=O)c2c1cccc2S(=O)(=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 7/20 0.46
TDP1 Q9NUW8 2/20 0.43
ALOX15 P16050 1/20 0.43
KMT2A Q03164 1/20 0.41
TYMS P04818 3/20 0.40
TSHR P16473 1/20 0.39
HTT P42858 1/20 0.39
FEN1 P39748 1/20 0.38
POLB P06746 1/20 0.38
GAA P10253 1/20 0.38
GFER P55789 1/20 0.38
ATM Q13315 1/20 0.36
ERAP1 Q9NZ08 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL766110 0.87 ALOX15 (0.46) TDP1ALOX15KMT2ATYMSTSHR
SCHEMBL24948318 0.82 ALOX15 (0.39) TDP1ALOX15KMT2ATYMSHTT
(Phenylsulfonyl)Benzene SCHEMBL424799 0.79 TDP1 (0.64) HTR6TDP1ALOX15KMT2ATYMS
SCHEMBL13241510 0.79 ALDH1A1 (0.57) HTR6TDP1ALOX15KMT2ATSHR
SCHEMBL31544427 0.79 ALDH1A1 (0.57) HTR6TDP1ALOX15KMT2ATSHR
SCHEMBL2281726 0.77 ALOX15 (0.43) TDP1ALOX15TYMSTSHRHTT
SCHEMBL17894508 0.77 TDP1 (0.43) TDP1ALOX15KMT2ATYMSTSHR
SCHEMBL1831245 0.77 ALOX15 (0.43) TDP1ALOX15KMT2ATYMSTSHR
SCHEMBL9793431 0.75 HTR6 (0.62) HTR6TDP1KMT2ATSHRHTT
SCHEMBL14629133 0.75 ALDH1A1 (0.45) HTR6TDP1KMT2ATSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7662903-B2 Thermoplastic polyimide and imide oligomer MANAC INC. (JP) 2010-02-16 US disclosed
US-20060247411-A1 Novel thermoplastic polyimide and inide oligomer MANAC INC. (JP) 2006-11-02 US disclosed
CN-1388904-A Polyimide resin optical element MITSUI CHEMICALS INC (JP) 2003-01-01 CN disclosed
US-6316170-B2 COATING, EXPOSURE, DEVELOPMENT AND HEAT TREATMENT KABUSHIKI KAISHA TOSHIBA (JP) 2001-11-13 US disclosed
US-20010006767-A1 Developing solution and method of forming polyimide pattern by using the developing solution YOSHIAKI KAWAMONZEN 2001-07-05 US disclosed
US-6183934-B1 FOE USE IN FORMATION OF PATTERN OF INSULATION FILM, PASSIVATION FILM, .ALPHA.-RAY SHIELDING FILM, OPTICAL WAVEGUIDE KABUSHIKI KAISHA TOSHIBA (JP) 2001-02-06 US disclosed
US-6001517-A A THERMOSETTING POLYMER WHICH CAN BE CURED THROUGH CYCLODEHYDRATION UPON HEATING AND A CURE ACCELERATOR WHICH CAN BE DEACTIVATED OF ITS CURE ACCELERATION PROPERTY BY IRRIDIATION OF LIGHT KABUSHIKI KAISHA TOSHIBA (JP) 1999-12-14 US disclosed
US-5530130-A DYEING PLASTICS BAYER AKTIENGESELLSCHAFT (DE) 1996-06-25 US disclosed
EP-0639624-A1 Phthaloperinone dyestuffs BAYER AG (DE) 1995-02-22 EP disclosed