Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | RECQL | P46063 | 5/20 | 0.42 |
| ▸ | IDO1 | P14902 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10554849 | 0.76 | MEN1 (0.43) | CA1CA2CA7CA9MAPT | |
| SCHEMBL19891984 | 0.70 | CA1 (0.53) | CA1CA2CA7CA9MAPT | |
| SCHEMBL3427256 | 0.69 | RAB9A (0.43) | CA1CA2CA7CA9MAPT | |
| SCHEMBL13898179 | 0.67 | CA1 (0.39) | CA1CA2CA7CA9MAPT | |
| SCHEMBL9389657 | 0.65 | MAOA (0.54) | CA1CA2CA7CA9MAPT | |
| SCHEMBL15642543 | 0.65 | CA1 (1.00) | CA1CA2CA7CA9MAPT | |
| SCHEMBL18971656 | 0.61 | CA1 (0.46) | CA1CA2CA7CA9MAPT | |
| SCHEMBL5080247 | 0.61 | CA1 (0.42) | CA1CA2CA7CA9MAPT | |
| SCHEMBL6824008 | 0.61 | CA1 (0.42) | CA1CA2CA7CA9MAPT | |
| Anthrarufin SCHEMBL187843 | 0.61 | MAOA (1.00) | MAPTKMT2AKDM4ERECQLIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180049997-A1 | CHOLESTERYL ESTER TRANSFER PROTEIN (CETP) INHIBITION IN THE TREATMENT OF CANCER | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2018-02-22 | — | — | US | disclosed |
| US-20180049997-A1 | CHOLESTERYL ESTER TRANSFER PROTEIN (CETP) INHIBITION IN THE TREATMENT OF CANCER | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2018-02-22 | — | — | US | disclosed |
| US-9890106-B2 | Anti-cancer lead molecule | KING ABDULLAH UNIVERSITY OF SCIENCE & TECHNOLOGY (SA) | 2018-02-13 | — | — | US | disclosed |
| WO-2016135633-A1 | CHOLESTERYL ESTER TRANSFER PROTEIN (CETP) INHIBITION IN THE TREATMENT OF CANCER | KING ABDULLAH UNIVERSITY OF SCIENCE & TECHNOLOGY (SA) | 2016-09-01 | — | — | WO | disclosed |
| US-20140107196-A1 | ANTI-CANCER LEAD MOLECULE | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2014-04-17 | — | — | US | disclosed |
| US-20140107196-A1 | ANTI-CANCER LEAD MOLECULE | KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) | 2014-04-17 | — | — | US | disclosed |
| US-20100028469-A1 | Extracts of Cranberry and Methods of Using Thereof | HERBALSCIENCE GROUP, LLC (US) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107196-A1 | ANTI-CANCER LEAD MOLECULE | ACAT2, BRCA1, ALPG | CA1 4395/4885CA2 4843/4885CA7 4567/4885 |
| US-20180049997-A1 | CHOLESTERYL ESTER TRANSFER PROTEIN (CETP) INHIBITION IN THE TREATMENT OF CANCER | CETP, LCAT, MTTP | CA1 3578/4885CA2 3018/4885CA7 2185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.