SCHEMBL3427256

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12253692	0.67	RAB9A (0.76)	RAB9ASMN1; SMN2NPC1ACHEKDM4E
	SCHEMBL10554849	0.66	MEN1 (0.43)	RAB9ASMN1; SMN2KDM4ELMNAALDH1A1
	SCHEMBL4226377	0.65	RAB9A (0.57)	RAB9ASMN1; SMN2NPC1ACHEKDM4E
	SCHEMBL6157005	0.65	RAB9A (0.53)	RAB9ASMN1; SMN2NPC1ACHEKDM4E
	SCHEMBL11807026	0.62	ALDH1A1 (0.43)	RAB9ASMN1; SMN2NPC1ACHEKDM4E
	SCHEMBL3278153	0.61	ALDH1A1 (0.60)	RAB9ASMN1; SMN2NPC1KDM4ELMNA
	SCHEMBL496978	0.61	RAB9A (1.00)	RAB9ASMN1; SMN2NPC1KDM4ELMNA
	SCHEMBL7786089	0.61	RAB9A (0.87)	RAB9ASMN1; SMN2NPC1KDM4ELMNA
	SCHEMBL7970824	0.61	RAB9A (0.65)	RAB9ASMN1; SMN2NPC1ACHEKDM4E
	SCHEMBL9181274	0.60	RAB9A (0.65)	RAB9ASMN1; SMN2NPC1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.