SCHEMBL319447

SCHEMBL319447

CCCCC(C#N)C(N)=O

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA2 P00918 8/20 0.50
CA1 P00915 4/20 0.50
MAPK1 P28482 1/20 0.38
SLC1A3 P43003 1/20 0.36
SLC1A2 P43004 1/20 0.36
SLC1A1 P43005 1/20 0.36
EPHX1 P07099 1/20 0.36
TSHR P16473 1/20 0.36
DPP7 Q9UHL4 2/20 0.35
SLC15A1 P46059 1/20 0.35
FDPS P14324 1/20 0.34
CTSS P25774 1/20 0.33
CTSK P43235 1/20 0.33
DPP4 P27487 1/20 0.33
DPP8 Q6V1X1 1/20 0.33
DPP9 Q86TI2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7294408 0.94 CA1 (0.44) CA2CA1SLC1A2SLC1A1EPHX1
SCHEMBL8649627 0.92 GPR84 (0.42) CA2CA1EPHX1FDPS
SCHEMBL4830821 0.92 GPR84 (0.42) CA2CA1EPHX1FDPS
SCHEMBL10883771 0.92 GPR84 (0.42) CA2CA1EPHX1FDPS
SCHEMBL319940 0.87
SCHEMBL27590374 0.83 FAAH (0.53)
SCHEMBL28866043 0.82 TSHR (0.41) CA2CA1SLC1A2EPHX1TSHR
SCHEMBL24099446 0.81 CPB2 (0.36) TSHRDPP7DPP4DPP8DPP9
SCHEMBL16016004 0.81 CA2 (0.39) CA2CA1MAPK1SLC1A3SLC1A2
SCHEMBL8014886 0.81 CA2 (0.52) CA2CA1MAPK1SLC1A3SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113956420-B Polyurethane yoga mat and preparation method thereof 南通恒嘉家居科技有限公司 2023-04-18 CN claimed
CN-113956420-A Polyurethane yoga mat and preparation method thereof 南通恒嘉家居科技有限公司 2022-01-21 CN claimed
US-10059823-B2 Additives for improving polyurethane foam performance EVONIK DEGUSSA GMBH (DE) 2018-08-28 US claimed
EP-2729510-B1 PROCESS FOR PRODUCING FLEXIBLE POLYURETHANE FOAM USING NATURAL OIL POLYOLS AIR PROD & CHEM (US) 2016-11-16 EP claimed
US-20160002426-A1 Additives for Improving Polyurethane Foam Performance AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-01-07 US claimed
EP-2591031-B1 PROCESS FOR PRODUCING FLEXIBLE POLYURETHANE FOAM AIR PROD & CHEM (US) 2015-06-17 EP claimed
EP-2738192-B1 Process for producing flexible polyurethane foam AIR PROD & CHEM (US) 2015-06-10 EP claimed
EP-2738192-A1 Process for producing flexible polyurethane foam AIR PRODUCTS AND CHEMICALS, INC. (US) 2014-06-04 EP claimed
EP-4680663-A1 METHOD OF RECYCLING A POLYAMIDE COMPOSITION INVISTA Textiles (U.K.) Limited (GB) 2026-01-21 EP disclosed
CN-120092044-A Process for recycling polyamide compositions 英威达纺织(英国)有限公司 2025-06-03 CN disclosed
WO-2024194724-A1 METHOD OF RECYCLING A POLYAMIDE COMPOSITION INV NYLON CHEMICALS AMERICAS, LLC (US) 2024-09-26 WO disclosed
EP-3494154-B1 POLYURETHANE FOAM FOR THIN WALL APPLICATIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2023-11-22 EP disclosed
CN-113956420-B Polyurethane yoga mat and preparation method thereof 南通恒嘉家居科技有限公司 2023-04-18 CN disclosed
CN-109563227-B Polyurethane foams for thin-walled applications 陶氏环球技术有限责任公司 2022-08-26 CN disclosed
US-20120178839-A1 Process For Producing Flexible Polyurethane Foam AIR PRODUCTS AND CHEMICALS, INC. (US) 2012-07-12 US disclosed
US-8178681-B2 methyl 3-methyl-2-{[2-oxo-1-(2-oxo-ethyl)-1,2,5,6,7,8,9,10-octahydro-cycloocta[b]pyridine-3-carbonyl]-amino}-butyrate; cannabinoid receptor agonist; antiinflammatory agent, immunostimulant, analgesic; atopic dermatitis; excellent in photostability, and have excellent transdermal and oral absorbency SHIONOGI & CO., LTD. (JP) 2012-05-15 US disclosed
WO-2012006539-A1 PROCESS FOR PRODUCING FLEXIBLE POLYURETHANE FOAM AIR PRODUCTS AND CHEMICALS, INC. (US) 2012-01-12 WO disclosed
US-20080103139-A1 3-Carbamoyl-2-Pyridone Derivative SHIONOGI & CO. LTD. (JP) 2008-05-01 US disclosed
EP-1806342-A1 3-CARBAMOYL-2-PYRIDONE DERIVATIVE SHIONOGI & CO., LTD. (JP) 2007-07-11 EP disclosed
US-3991054-A FOR POLYESTERS BASF AKTIENGESELLSCHAFT (DT) 1976-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080103139-A1 3-Carbamoyl-2-Pyridone Derivative CNR1, CNR2, HRH4 CA2 703/4885CA1 2935/4885MAPK1 1122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.