SCHEMBL3196358

SCHEMBL3196358

C#CCOc1cc(C(=O)Nc2c(Cl)cc(Cl)cc2C(=O)NC(C)C)n(-c2ncccc2Cl)n1

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2B6 P20813 1/20 0.34
CAPN1 P07384 1/20 0.33
CNR1 P21554 2/20 0.33
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
HPGD P15428 1/20 0.32
CNR2 P34972 1/20 0.32
ALPL P05186 1/20 0.32
NTRK1 P04629 10/20 0.32
GCK P35557 1/20 0.32
KCNH2 Q12809 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL782499 0.86 CNR1 (0.36) CAPN1CNR1ALDH1A1POLBMAPT
SCHEMBL3196343 0.86 CNR1 (0.33) CAPN1CNR1ALDH1A1POLBMAPT
SCHEMBL782468 0.85 DHODH (0.41) CAPN1CNR1ALDH1A1POLBMAPT
SCHEMBL31256508 0.85 DHODH (0.41) CAPN1CNR1ALDH1A1POLBMAPT
SCHEMBL15743795 0.84 CAPN1 (0.34) CAPN1CNR1ALDH1A1POLBMAPT
SCHEMBL30415001 0.83 GRM5 (0.34) CNR1ALDH1A1POLBMAPTPKM
SCHEMBL29039023 0.83 GRM5 (0.34) CNR1ALDH1A1POLBMAPTPKM
SCHEMBL30398530 0.83 KMT2A (0.33) CNR1
SCHEMBL29039024 0.83 POLB (0.34) CNR1ALDH1A1POLBMAPTPKM
SCHEMBL28491735 0.83 CNR1 (0.32) CAPN1CNR1ALDH1A1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7666882-B2 1-(3-Chloro-2-pyridinyl)-N-[2,4-dichloro-6-[[(1-methylethyl)amino]carbonyl]phenyl]-3-(2-propynyloxy)-1H-pyrazole-5-carboxamide; controlling an invertebrate pest; less costly, less toxic, environmentally safer E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-23 US disclosed
US-20060014808-A1 Novel anthranilamide insecticides E. I. DU PONT DE NEMOURS AND COMPANY 2006-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060014808-A1 Novel anthranilamide insecticides RTN4, ANTXR2, SCN4A CYP2B6 8/4885CAPN1 3467/4885CNR1 232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.