Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | RBP4 | P02753 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 2/20 | 0.31 |
| ▸ | ACLY | P53396 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3199797 | 0.92 | MALT1 (0.34) | CNR1POLBKMT2APDE4ARBP4 | |
| SCHEMBL782499 | 0.87 | CNR1 (0.36) | CNR1TSHRCNR2ALDH1A1POLB | |
| SCHEMBL3196358 | 0.86 | CYP2B6 (0.34) | CNR1CNR2ALDH1A1POLBMAPT | |
| SCHEMBL31256508 | 0.85 | DHODH (0.41) | CNR1TSHRCNR2ALDH1A1POLB | |
| SCHEMBL782468 | 0.85 | DHODH (0.41) | CNR1TSHRCNR2ALDH1A1POLB | |
| SCHEMBL30415001 | 0.84 | GRM5 (0.34) | CNR1CNR2ALDH1A1POLBMAPT | |
| SCHEMBL29039023 | 0.84 | GRM5 (0.34) | CNR1CNR2ALDH1A1POLBMAPT | |
| SCHEMBL29039024 | 0.83 | POLB (0.34) | CNR1TSHRALDH1A1POLBMAPT | |
| SCHEMBL30398530 | 0.83 | KMT2A (0.33) | CNR1KMT2ARBP4DHODH | |
| SCHEMBL28491735 | 0.83 | CNR1 (0.32) | CNR1CNR2ALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7666882-B2 | 1-(3-Chloro-2-pyridinyl)-N-[2,4-dichloro-6-[[(1-methylethyl)amino]carbonyl]phenyl]-3-(2-propynyloxy)-1H-pyrazole-5-carboxamide; controlling an invertebrate pest; less costly, less toxic, environmentally safer | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-02-23 | — | — | US | disclosed |
| US-20060014808-A1 | Novel anthranilamide insecticides | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060014808-A1 | Novel anthranilamide insecticides | RTN4, ANTXR2, SCN4A | CNR1 232/4885TSHR 2354/4885CNR2 329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.