Sugi Predict

Sugi Predict / Compounds / SCHEMBL782468

SCHEMBL782468

SCHEMBL782468

CC(C)NC(=O)c1cc(Cl)cc(Cl)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.70

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ DHODH Q02127 3/20 0.41
▸ CNR1 P21554 3/20 0.35
▸ PDE4A P27815 2/20 0.35
▸ KCNH2 Q12809 1/20 0.35
▸ CNR2 P34972 3/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ POLB P06746 1/20 0.35
▸ MAPT P10636 1/20 0.35
▸ PKM P14618 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ CAPN1 P07384 1/20 0.34
▸ RECQL P46063 1/20 0.34
▸ RBP4 P02753 1/20 0.33
▸ TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31256508 1.00 DHODH (0.41) DHODHCNR1PDE4AKCNH2CNR2
SCHEMBL16622520 0.93 DHODH (0.40) DHODHKCNH2CAPN1RBP4
SCHEMBL782232 0.93 DHODH (0.43) DHODHCNR1PDE4AKCNH2CNR2
SCHEMBL10140214 0.93 DHODH (0.40) DHODHCNR1PDE4AKCNH2CNR2
SCHEMBL26967937 0.92 DHODH (0.39) DHODHCNR1CNR2ALDH1A1POLB
SCHEMBL14542618 0.91 DHODH (0.40) DHODHRBP4
SCHEMBL782499 0.91 CNR1 (0.36) DHODHCNR1PDE4AKCNH2CNR2
SCHEMBL29416624 0.90 IDO1 (0.38) DHODHCNR1CNR2
SCHEMBL196132 0.90 IDO1 (0.38) DHODHCNR1CNR2
SCHEMBL782140 0.90 DHODH (0.42) DHODHRBP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110066270-B Polyamide compound and preparation method and application thereof 湖南化工研究院有限公司 2021-02-26 — — CN disclosed
US-10405548-B2 Fungicidal compositions SYNGENTA CROP PROTECTION LLC (US) 2019-09-10 — — US disclosed
EP-2547665-B1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-07-04 — — EP disclosed
US-9949482-B2 Fungicidal compositions SYNGENTA CROP PROTECTION, LLC (US) 2018-04-24 — — US disclosed
US-9771365-B2 Spiroheterocyclic N-oxypiperidines as pesticides SYNGENTA PARTICIPATIONS AG (CH) 2017-09-26 — — US disclosed
US-9771365-B2 Spiroheterocyclic N-oxypiperidines as pesticides SYNGENTA PARTICIPATIONS AG (CH) 2017-09-26 — — US disclosed
US-20170071205-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION, LLC (US) 2017-03-16 — — US disclosed
US-20170027173-A1 INSECTICIDAL COMPOUNDS SYNGENTA CROP PROTECTION, LLC (US) 2017-02-02 — — US disclosed
US-20170027173-A1 INSECTICIDAL COMPOUNDS SYNGENTA CROP PROTECTION, LLC (US) 2017-02-02 — — US disclosed
EP-2723723-B1 N-OXY PYRAZOLO-TRIAZEPINE-DIONE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2017-02-01 — — EP disclosed
US-20070244073-A1 Pesticidal Mixtures SYNGENTA CROP PROTECTION, INC. (US) 2007-10-18 — — US disclosed
US-20070244073-A1 Pesticidal Mixtures SYNGENTA CROP PROTECTION, INC. (US) 2007-10-18 — — US disclosed
US-20070232598-A1 Combination of Active Substances with Insecticidal Properties BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-10-04 — — US disclosed
US-20070232598-A1 Combination of Active Substances with Insecticidal Properties BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-10-04 — — US disclosed
WO-2007093402-A1 PESTICIDES CONTAINING A BICYCLIC BISAMIDE STRUCTURE SYNGENTA PARTICIPATIONS AG (CH) 2007-08-23 — — WO disclosed
WO-2007080131-A2 ANTHRANILAMIDE DERIVATIVES AND THEIR USE FOR THE CONTROL OF INSECTS AND ACARI SYNGENTA PARTICIPATIONS AG (CH) 2007-07-19 — — WO disclosed
US-20070142327-A1 Active compound combinations having insecticidal properties BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-06-21 — — US disclosed
US-20070142327-A1 Active compound combinations having insecticidal properties BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2007-06-21 — — US disclosed
WO-2007020050-A2 BICYCLIC BISAMIDE DERIVATIVES AND USE THEREOF AS INSECTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2007-02-22 — — WO disclosed
WO-2007009661-A2 PESTICIDAL MIXTURES CONTAINING BICYCLIC ANTHRANILAMIDES SYNGENTA PARTICIPATIONS AG (CH) 2007-01-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070142327-A1 Active compound combinations having insecticidal properties ACHE, ANTXR2, NANP DHODH 2787/4885CNR1 1471/4885PDE4A 75/4885
US-20170027173-A1 INSECTICIDAL COMPOUNDS ACHE, AADAC, CASP3 DHODH 1693/4885CNR1 1508/4885PDE4A 937/4885
US-20070232598-A1 Combination of Active Substances with Insecticidal Properties ACHE, CHRM3, CHRNA2 DHODH 3666/4885CNR1 44/4885PDE4A 341/4885
US-20070244073-A1 Pesticidal Mixtures ACHE, ATL3, BPHL DHODH 2761/4885CNR1 1735/4885PDE4A 501/4885
US-10405548-B2 Fungicidal compositions PIK3C3, CYP51A1, CYP1B1 DHODH 874/4885CNR1 3467/4885PDE4A 504/4885
US-20170071205-A1 FUNGICIDAL COMPOSITIONS PIK3C3, CYP51A1, CYP1B1 DHODH 874/4885CNR1 3467/4885PDE4A 504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.