SCHEMBL3196407

SCHEMBL3196407

Clc1cc(OCc2ccccc2)cc(Cl)c1Cl

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
CYP1A2 P05177 2/20 0.52
LMNA P02545 1/20 0.52
PTGS1 P23219 1/20 0.52
SLC6A2 P23975 1/20 0.52
CYP2C19 P33261 1/20 0.52
PTGS2 P35354 1/20 0.52
SLC6A3 Q01959 1/20 0.52
HIF1A Q16665 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
MAOB P27338 6/20 0.50
RAB9A P51151 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
GAA P10253 1/20 0.50
MAPT P10636 1/20 0.50
MAOA P21397 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
NPC1 O15118 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31725679 0.86 APP (0.53) ALOX5MEN1KMT2ACYP1A2LMNA
SCHEMBL10665635 0.85 MAOB (0.53) ALOX5MEN1KMT2ACYP1A2LMNA
SCHEMBL21538106 0.85 MAPT (0.52) ALOX5MEN1KMT2ACYP1A2LMNA
SCHEMBL2446166 0.85 CYP1A2 (0.58) ALOX5MEN1KMT2ACYP1A2LMNA
SCHEMBL11128958 0.84 APP (0.50) ALOX5MEN1KMT2ACYP1A2LMNA
SCHEMBL4674930 0.83 MEN1 (0.70) ALOX5MEN1KMT2ACYP1A2LMNA
SCHEMBL208614 0.82 MEN1 (0.51) ALOX5MEN1KMT2ACYP1A2LMNA
SCHEMBL21538105 0.82 ALOX5 (0.51) ALOX5MEN1KMT2ACYP1A2LMNA
SCHEMBL13955217 0.82 MEN1 (0.47) ALOX5MEN1KMT2ACYP1A2LMNA
SCHEMBL210025 0.82 MAOB (0.49) ALOX5MEN1KMT2ACYP1A2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7671055-B2 surprisingly active in the control of insects and acarids; admixture with pesticides, plant growth regulators, fertilizers and soil conditioners FMC CORPORATION (US) 2010-03-02 US disclosed
US-20080261993-A1 Insecticidal 3-(Dihaloalkenyl) Phenyl Derivatives BAYER CROPSCIENCE AG (DE) 2008-10-23 US disclosed
EP-1805152-A2 INSECTICIDAL 3-(DIHALOALKENYL) PHENYL DERIVATIVES Bayer CropScience AG (DE) 2007-07-11 EP disclosed
WO-2006047438-A2 INSECTICIDAL 3-(DIHALOALKENYL) PHENYL DERIVATIVES BAYER CROPSCIENCE AG (DE) 2006-05-04 WO disclosed
US-4769370-A BRAIN INJURY TREATMENT MERCK & CO., INC. (US) 1988-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080261993-A1 Insecticidal 3-(Dihaloalkenyl) Phenyl Derivatives DDT, L3MBTL4, L3MBTL3 ALOX5 2471/4885MEN1 3726/4885KMT2A 3136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.