Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3196865 | 0.77 | ALDH1A1 (0.35) | ALDH1A1MAPK1ESR2 | |
| SCHEMBL5003716 | 0.73 | ALDH1A1 (0.30) | ALDH1A1MAPK1 | |
| SCHEMBL2525984 | 0.72 | PDCD1 (0.33) | ALDH1A1MAPK1ESR2 | |
| SCHEMBL7943368 | 0.71 | PDCD1 (0.33) | ALDH1A1MAPK1ESR2 | |
| SCHEMBL3206259 | 0.69 | — | — | |
| SCHEMBL6553568 | 0.69 | PDCD1 (0.31) | ALDH1A1MAPK1 | |
| SCHEMBL20496069 | 0.69 | PDCD1 (0.31) | ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL27670353 | 0.68 | ESR2 (0.36) | ALDH1A1MAPK1ESR2 | |
| Hydrochloric Acid SCHEMBL5511524 | 0.68 | ESR2 (0.32) | ESR2 | |
| SCHEMBL21980379 | 0.68 | PDCD1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960411-B1 | HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2016-08-31 | — | — | EP | disclosed |
| US-7667064-B2 | high weight average molecular weight while having a relatively narrow molecular weight distribution, resulting in high strength polyolefin; e.g. dimethylsilandiyl(eta 5-2-methyl-4-bromoinden-1-yl)(N-tert-butylamido)titanium dichloride | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-02-23 | — | — | US | disclosed |
| EP-1960411-A1 | HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | ExxonMobil Chemical Patents Inc. (US) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007070040-A1 | HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |
| US-20070135594-A1 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135594-A1 | Halogen substituted metallocene compounds for olefin polymerization | MLX, AP1M1, AP2M1 | ALDH1A1 1617/4885MAPK1 1102/4885ESR2 1128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.