Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11106673 | 0.98 | ALDH1A1 (0.43) | ALDH1A1HSD17B10CFTRCHEK1MET | |
| SCHEMBL13014586 | 0.82 | ALDH1A1 (0.49) | ALDH1A1HSD17B10KDM4EPOLBGAA | |
| Hydrochloric Acid SCHEMBL3222319 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HSD17B10KDM4EPOLBGAA | |
| SCHEMBL3215283 | 0.80 | TSHR (0.38) | ALDH1A1HSD17B10CHEK1METGSK3B | |
| SCHEMBL3211635 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HSD17B10KDM4EPOLBKMT2A | |
| SCHEMBL11975682 | 0.79 | KDM4E (0.40) | ALDH1A1HSD17B10CFTRCHEK1MET | |
| SCHEMBL23413048 | 0.78 | ALDH1A1 (0.46) | ALDH1A1HSD17B10CFTRCHEK1MET | |
| SCHEMBL6615690 | 0.78 | KDM4E (0.40) | ALDH1A1HSD17B10KDM4EGAAKMT2A | |
| SCHEMBL3199729 | 0.78 | CA2 (0.46) | ALDH1A1HSD17B10CFTRCHEK1MET | |
| SCHEMBL3230676 | 0.77 | KDM4E (0.57) | ALDH1A1HSD17B10CFTRCHEK1MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858805-B2 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | BAYER AKTIENGESELLSCHAFT (DE) | 2010-12-28 | — | — | US | disclosed |
| US-20100056798-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | BAYER CROPSCIENCE AG (DE) | 2010-03-04 | — | — | US | disclosed |
| US-7642221-B2 | herbicides; preparation from chemical intermediates; treating the crops | BAYER AKTIENGESELLSCHAFT (DE) | 2010-01-05 | — | — | US | disclosed |
| US-6964939-B1 | Substituted thiene-3-yl-sulfonyl amino(thio)carbonyl-triazolin(thi)ones | BAYER AKTIENGESELLSCHAFT (DE) | 2005-11-15 | — | — | US | disclosed |
| US-20050130843-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056798-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | TST, SULT1E1, CCNE2 | ALDH1A1 975/4885HSD17B10 2079/4885CFTR 1421/4885 |
| US-20050130843-A1 | Substituted thien-3-yl-sulphonylamino(thio)carbonyl-triazolin(ethi)ones | TST, SULT1E1, SULT2A1 | ALDH1A1 597/4885HSD17B10 1783/4885CFTR 1679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.