Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.52 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536213 | 0.86 | APP (0.53) | PDE10APRKCICASP1CA1CA2 | |
| SCHEMBL18509676 | 0.80 | ALDH1A1 (0.50) | PDE10APRKCICASP1TSHRACHE | |
| SCHEMBL7756464 | 0.77 | PRKCI (0.56) | PDE10APRKCICASP1CA1CA2 | |
| SCHEMBL7884400 | 0.75 | PDE10A (0.45) | PDE10APRKCICASP1CA1CA2 | |
| SCHEMBL15490156 | 0.73 | TSHR (0.52) | PDE10APRKCICASP1CA1CA2 | |
| Trimethylammonium SCHEMBL27731909 | 0.73 | PDE10A (0.86) | PDE10APRKCICASP1CA1CA2 | |
| Hydrochloric Acid SCHEMBL15486297 | 0.71 | TSHR (0.50) | PDE10APRKCICASP1CA1CA2 | |
| SCHEMBL6752755 | 0.71 | PRKCI (0.42) | PDE10APRKCICASP1CA1CA2 | |
| Ethane SCHEMBL11239269 | 0.70 | CASP1 (0.61) | PDE10APRKCICASP1CA1CA2 | |
| SCHEMBL3338265 | 0.70 | PRKCI (0.69) | PDE10APRKCICASP1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453476-B1 | NOVEL OXIDATION DYES COMPRISING 2,4-DICHLORO-3-AMINOPHENOL | HENKEL KGAA (DE) | 2006-05-03 | — | — | EP | claimed |
| EP-1309540-B1 | OXIDIZING COLORANT | HENKEL KGAA (DE) | 2005-11-02 | — | — | EP | claimed |
| EP-1309540-A1 | OXIDIZING COLORANT | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-05-14 | — | — | EP | claimed |
| WO-2002010118-A1 | OXIDIZING COLORANT | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-02-07 | — | — | WO | claimed |
| EP-2037871-B1 | OXIDATION DYES FOR DYEING KERATIN FIBERS CONTAINING ATMOSPHERIC OXYGEN AS THE ONLY OXIDIZING AGENT | HENKEL AG & CO KGAA (DE) | 2016-02-24 | — | — | EP | disclosed |
| EP-2934462-A2 | TWO-PHASE DEVELOPER FOR OXIDATIVE COLOR CHANGING AGENTS | Henkel AG&Co. KGAA (DE) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014095458-A2 | TWO-PHASE DEVELOPER FOR OXIDATIVE COLOR CHANGING AGENTS | HENKEL AG & CO. KGAA (DE) | 2014-06-26 | — | — | WO | disclosed |
| EP-1536757-B1 | HAIR TREATMENT AGENT | HENKEL AG & CO KGAA (DE) | 2013-10-23 | — | — | EP | disclosed |
| US-20100047202-A1 | Hair-Conditioning Agents Containing Selected Cationic Polymers and Water-Soluble Silicones | HENKEL AG & CO.KGAA (DE) | 2010-02-25 | — | — | US | disclosed |
| EP-2037871-A1 | OXIDATION DYES FOR DYEING KERATIN FIBERS CONTAINING ATMOSPHERIC OXYGEN AS THE ONLY OXIDIZING AGENT | Henkel AG & Co. KGaA (DE) | 2009-03-25 | — | — | EP | disclosed |
| WO-2008003686-A1 | OXIDATION DYES FOR DYEING KERATIN FIBERS CONTAINING ATMOSPHERIC OXYGEN AS THE ONLY OXIDIZING AGENT | HENKEL AG & CO. KGAA (DE) | 2008-01-10 | — | — | WO | disclosed |
| EP-1406577-B1 | NOVEL COUPLER COMPONENTS FOR OXIDATIVE HAIR COLOURING | HENKEL KGAA (DE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2002039966-A2 | ENZYMATIC COLORING AGENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-05-23 | — | — | WO | disclosed |
| WO-2002010118-A1 | OXIDIZING COLORANT | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-02-07 | — | — | WO | disclosed |
| WO-2002005767-A1 | OXIDISED HAIR COLOURING AGENTS CONTAINING AT LEAST ONE DISUBSTITUITED 2.4-DIAMINO PHENYL ETHER AS A COUPLING COMPONENT | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-01-24 | — | — | WO | disclosed |
| WO-2002006207-A2 | NOVEL COUPLING COMPONENTS FOR OXIDATION COLOURING AGENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-01-24 | — | — | WO | disclosed |
| WO-2001097766-A2 | OXIDISED HAIR DYE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-12-27 | — | — | WO | disclosed |
| WO-2001097756-A2 | NOVEL COUPLING COMPONENT FOR OXIDATIVE HAIR DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-12-27 | — | — | WO | disclosed |
| WO-2001098276-A1 | PARA-AMINOPHENOL DERIVATIVES AND THEIR USE AS DEVELOPERS FOR PRODUCING OXIDATION COLORATIONS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-12-27 | — | — | WO | disclosed |
| WO-2001093818-A1 | OXIDATION DYEING METHOD FOR KERATINOUS FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100047202-A1 | Hair-Conditioning Agents Containing Selected Cationic Polymers and Water-Soluble Silicones | KRT18, CUTA, HDAC10 | PDE10A 2257/4885PRKCI 545/4885CASP1 3377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.