Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.52 |
| ▸ | PRKCI | P41743 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3197665 | 0.86 | PDE10A (0.52) | APPPDE10APRKCICASP1CA1 | |
| SCHEMBL15490156 | 0.82 | TSHR (0.52) | APPPDE10APRKCICASP1CA1 | |
| Hydrochloric Acid SCHEMBL15486297 | 0.80 | TSHR (0.50) | APPPDE10APRKCICASP1CA1 | |
| SCHEMBL11811790 | 0.78 | CYP3A4 (0.46) | APPPDE10ACASP1TSHRACHE | |
| SCHEMBL7756464 | 0.77 | PRKCI (0.56) | PDE10APRKCICASP1CA1CA2 | |
| SCHEMBL1708820 | 0.76 | CHEK1 (0.45) | PDE10APRKCICASP1TSHRMAPT | |
| SCHEMBL9079910 | 0.76 | ALDH1A1 (0.61) | APPCASP1CA1CA2TSHR | |
| SCHEMBL7884400 | 0.75 | PDE10A (0.45) | PDE10APRKCICASP1CA1CA2 | |
| SCHEMBL31158047 | 0.74 | TRPA1 (0.54) | APPCASP1TSHRMAPTGAA | |
| SCHEMBL636392 | 0.74 | TRPA1 (0.54) | APPCASP1TSHRMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0868165-A1 | MEANS AND METHOD FOR TINTING KERATIN FIBERS | Wella Aktiengesellschaft (DE) | 1998-10-07 | — | — | EP | claimed |
| WO-1998017235-A1 | MEANS AND METHOD FOR TINTING KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 1998-04-30 | — | — | WO | claimed |
| CN-110330479-A | A kind of antitumoral compounds and application thereof as AXL inhibitor | 南京华威医药科技集团有限公司 | 2019-10-15 | — | — | CN | disclosed |
| WO-2017159484-A1 | 2,4-DIAMINOPHENOL DERIVATIVE, AND AGENT FOR INHIBITING AGGREGATION OF TAU AND/OR AMYLOID β | 学校法人同志社 | 2017-09-21 | — | — | WO | disclosed |
| CN-1085218-C | Olefin polymerization catalyst | ASAHI CHEMICAL IND (JP) | 2002-05-22 | — | — | CN | disclosed |
| EP-0868165-A1 | MEANS AND METHOD FOR TINTING KERATIN FIBERS | Wella Aktiengesellschaft (DE) | 1998-10-07 | — | — | EP | disclosed |
| WO-1998017235-A1 | MEANS AND METHOD FOR TINTING KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 1998-04-30 | — | — | WO | disclosed |
| US-4517005-A | Aminophenol urease inhibitors and urease inhibited urea based fertilizer compositions | ALLIED CORPORATION (US) | 1985-05-14 | — | — | US | disclosed |