SCHEMBL3197899

SCHEMBL3197899

CO[Si](CCCn1cccn1)(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.36
HTR1A P08908 1/20 0.35
HTR2C P28335 1/20 0.35
THRB P10828 2/20 0.35
TLR8 Q9NR97 1/20 0.35
TLR7 Q9NYK1 1/20 0.35
DAO P14920 1/20 0.34
ALDH1A1 P00352 4/20 0.33
GAA P10253 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
KMT2A Q03164 1/20 0.33
FDPS P14324 1/20 0.33
KDM4E B2RXH2 2/20 0.32
MAPT P10636 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7100687 0.77 DAO (0.43) THRBTLR8TLR7DAOALDH1A1
SCHEMBL12811510 0.77 FDPS (0.38) LMNAHTR1AHTR2CTHRBTLR8
SCHEMBL152255 0.76 LMNA (0.33) LMNAKMT2A
SCHEMBL796651 0.76
SCHEMBL13017013 0.74 CYP19A1 (0.34) LMNA
Bromide SCHEMBL556174 0.74 TLR8 (0.44) THRBTLR8TLR7DAOALDH1A1
SCHEMBL45207 0.74 TLR8 (0.44) LMNATLR8TLR7DAOALDH1A1
Hydrochloric Acid SCHEMBL6736377 0.74 TLR8 (0.44) TLR8TLR7DAOALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL557786 0.74 TLR8 (0.44) TLR8TLR7DAOALDH1A1L3MBTL1
SCHEMBL6114991 0.72 TBXAS1 (0.47) LMNATLR8TLR7DAOKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120157579-A1 Azolium Ionomer Derivatives of Halogenated Polymers QUEEN'S UNIVERSITY AT KINGSTON (CA) 2012-06-21 US claimed
WO-2012075574-A1 AZOLIUM IONOMER DERIVATIVES OF HALOGENATED POLYMERS QUEEN'S UNIVERSITY AT KINGSTON (CA) 2012-06-14 WO claimed
WO-2012113068-A1 EMULSIONS OF FREE-RADICAL CURABLE ELASTOMERS QUEEN'S UNIVERSITY AT KINGSTON (CA) 2012-08-30 WO disclosed
US-20120157579-A1 Azolium Ionomer Derivatives of Halogenated Polymers QUEEN'S UNIVERSITY AT KINGSTON (CA) 2012-06-21 US disclosed
US-20120157579-A1 Azolium Ionomer Derivatives of Halogenated Polymers QUEEN'S UNIVERSITY AT KINGSTON (CA) 2012-06-21 US disclosed
WO-2012075574-A1 AZOLIUM IONOMER DERIVATIVES OF HALOGENATED POLYMERS QUEEN'S UNIVERSITY AT KINGSTON (CA) 2012-06-14 WO disclosed
US-7670492-B2 Method of removing a metal ion from a water stream using organo-ceramic composite materials SYRACUSE UNIVERSITY (US) 2010-03-02 US disclosed
US-20080164215-A1 ORGANO-CERAMIC COMPOSITE MATERIALS, THEIR USE AS ADSORBENTS, AND METHODS OF MAKING THE SAME SYRACUSE UNIVERSITY (US) 2008-07-10 US disclosed
US-7358318-B1 Organo-ceramic composite materials, their use as adsorbents, and methods of making the same SYRACUSE UNIVERSITY (US) 2008-04-15 US disclosed
US-7358318-B1 Organo-ceramic composite materials, their use as adsorbents, and methods of making the same SYRACUSE UNIVERSITY (US) 2008-04-15 US disclosed
WO-2000069949-A1 ORGANO-CERAMIC COMPOSITE MATERIALS, THEIR USE AS ADSORBENTS, AND METHODS OF MAKING THE SAME SYRACUSE UNIVERSITY (US) 2000-11-23 WO disclosed