Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 13/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3213867 | 0.87 | KMT2A (0.51) | TRPV1HSD11B1KMT2AMEN1CNR1 | |
| SCHEMBL3212924 | 0.85 | HSD11B1 (0.65) | TRPV1HSD11B1LMNA | |
| SCHEMBL3224328 | 0.83 | HSD11B1 (0.67) | TRPV1HSD11B1KMT2AMEN1LMNA | |
| SCHEMBL3209708 | 0.82 | MEN1 (0.47) | TRPV1HSD11B1KMT2AMEN1LMNA | |
| SCHEMBL13489663 | 0.82 | TRPV1 (0.53) | TRPV1HSD11B1KMT2ALMNA | |
| SCHEMBL3225849 | 0.81 | RBP4 (0.52) | KMT2AMEN1ATMCNR1 | |
| SCHEMBL3205481 | 0.79 | HSD11B1 (0.67) | TRPV1HSD11B1KMT2AMEN1 | |
| SCHEMBL3213922 | 0.78 | HSD11B1 (0.67) | HSD11B1KMT2AMEN1LMNAGAA | |
| SCHEMBL1690182 | 0.75 | TRPV1 (0.53) | TRPV1HSD11B1 | |
| SCHEMBL1459053 | 0.73 | TRPV1 (0.66) | TRPV1HSD11B1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029648-A1 | 11-Beta HSD1 Inhibitors | XIANG JASON SHAOYUN | 2010-02-04 | — | — | US | disclosed |
| US-7632838-B2 | 11-beta HSD1 inhibitors | WYETH (US) | 2009-12-15 | — | — | US | disclosed |
| US-20070219198-A1 | 11-Beta HSD 1 inhibitors | WYETH (US) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029648-A1 | 11-Beta HSD1 Inhibitors | HSD11B1, HSD3B1, HSD11B2 | TRPV1 4793/4885HSD11B1 1/4885KMT2A 1609/4885 |
| US-20070219198-A1 | 11-Beta HSD 1 inhibitors | HSD11B1, HSD11B2, HSD3B1 | TRPV1 4707/4885HSD11B1 1/4885KMT2A 1591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.