Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.35 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28363774 | 0.88 | TSHR (0.40) | TSHRALOX15APEX1BRD4HDAC4 | |
| SCHEMBL2637053 | 0.81 | MAPT (0.33) | TSHRALOX15APEX1HIF1ATDP1 | |
| SCHEMBL8173084 | 0.81 | IDO1 (0.39) | HDAC4HDAC7HDAC5IDO1TDO2 | |
| SCHEMBL64259 | 0.80 | LMNA (0.43) | TSHRMAPK1LMNAALDH1A1CYP2D6 | |
| SCHEMBL5745417 | 0.80 | LMNA (0.43) | TSHRMAPK1LMNAALDH1A1CYP2D6 | |
| SCHEMBL28980083 | 0.77 | ADRB2 (0.45) | TSHRALOX15BRD4HDAC4HDAC7 | |
| SCHEMBL6205149 | 0.73 | ADRB2 (0.44) | TSHRALOX15BRD4HDAC4HDAC7 | |
| SCHEMBL970779 | 0.72 | BRD4 (0.38) | TSHRALOX15APEX1BRD4HDAC4 | |
| SCHEMBL9972333 | 0.71 | IDO1 (0.40) | TSHRALOX15APEX1BRD4HDAC4 | |
| SCHEMBL970778 | 0.71 | TSHR (0.43) | TSHRALOX15APEX1BRD4HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106883266-B | Preparation method of 1- (4-chlorphenyl) -2-cyclopropyl-1-acetone and intermediate thereof | 江苏七洲绿色化工股份有限公司 | 2020-03-17 | — | — | CN | claimed |
| US-8211286-B2 | Electrolyte and method for depositing decorative and technical layers of black ruthenium | Umicore Galvotechnik GmbH (DE) | 2012-07-03 | — | — | US | claimed |
| US-20100051468-A1 | ELECTROLYTE AND METHOD FOR DEPOSITING DECORATIVE AND TECHNICAL LAYERS OF BLACK RUTHENIUM | UMICORE GALVANOTECHNIK GMBH (DE) | 2010-03-04 | — | — | US | claimed |
| CN-115385784-B | Preparation method of 1- (4-chlorophenyl) -2-cyclopropyl-1-acetone | 顺毅股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-115385784-A | Preparation method of 1- (4-chlorphenyl) -2-cyclopropyl-1-acetone | 顺毅股份有限公司 | 2022-11-25 | — | — | CN | disclosed |
| CN-106883266-B | Preparation method of 1- (4-chlorphenyl) -2-cyclopropyl-1-acetone and intermediate thereof | 江苏七洲绿色化工股份有限公司 | 2020-03-17 | — | — | CN | disclosed |