Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | TDO2 | P48775 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12858755 | 0.76 | LMNA (0.41) | TSHRMAPK1HIF1ALMNA | |
| SCHEMBL6205149 | 0.74 | ADRB2 (0.44) | IDO1TDO2TSHRMAPK1HIF1A | |
| SCHEMBL3199543 | 0.71 | TSHR (0.42) | IDO1TDO2TSHRMAPK1HIF1A | |
| SCHEMBL9972324 | 0.71 | TP53 (0.46) | IDO1TDO2TSHRTDP1LMNA | |
| SCHEMBL970779 | 0.70 | BRD4 (0.38) | IDO1TDO2TSHRMAPK1HIF1A | |
| SCHEMBL3688149 | 0.69 | TSHR (0.50) | IDO1TDO2TSHRMAPK1HIF1A | |
| SCHEMBL1426754 | 0.69 | TSHR (0.50) | IDO1TDO2TSHRMAPK1HIF1A | |
| SCHEMBL10654649 | 0.69 | TSHR (0.50) | IDO1TDO2TSHRMAPK1HIF1A | |
| SCHEMBL28363774 | 0.68 | TSHR (0.40) | IDO1TDO2TSHRMAPK1HIF1A | |
| SCHEMBL11780285 | 0.67 | TSHR (0.55) | IDO1TDO2TSHRMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202877-B2 | Aminopyrimidinamides as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-06-19 | — | — | US | disclosed |
| US-20100298267-A1 | AMINOPYRIMIDINAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (US) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298267-A1 | AMINOPYRIMIDINAMIDES AS PESTICIDES | DDT, NPEPPS, PTMS | IDO1 668/4885TDO2 872/4885TSHR 3137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.