SCHEMBL3202138

SCHEMBL3202138

Cc1cc(OC(C)(C)C)cc(C)c1S(OS(=O)(=O)c1ccc(C(F)(F)F)cc1C(F)(F)F)(c1ccccc1)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLQ O75417 1/20 0.34
NPSR1 Q6W5P4 3/20 0.34
KDM4E B2RXH2 2/20 0.34
MAPT P10636 2/20 0.34
LMNA P02545 1/20 0.34
ALDH1A1 P00352 3/20 0.33
HSD11B1 P28845 3/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
MCOLN3 Q8TDD5 1/20 0.32
CYP3A4 P08684 4/20 0.32
CYP2C19 P33261 3/20 0.32
CYP2D6 P10635 2/20 0.32
CYP1A2 P05177 2/20 0.32
NR3C1 P04150 1/20 0.32
PGR P06401 1/20 0.32
AR P10275 1/20 0.32
ESR2 Q92731 1/20 0.32
MCL1 Q07820 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3201801 0.90 CYP3A4 (0.34) POLQKDM4EMAPTLMNAALDH1A1
SCHEMBL3183558 0.89 HSD11B1 (0.33) NPSR1KDM4EMAPTLMNAALDH1A1
SCHEMBL3190769 0.89 POLQ (0.37) POLQKDM4EMAPTLMNAALDH1A1
SCHEMBL3199737 0.89 CYP3A4 (0.42) POLQNPSR1KDM4EMAPTLMNA
SCHEMBL3202334 0.88 MCL1 (0.37) POLQNPSR1KDM4EMAPTLMNA
SCHEMBL3182063 0.87 HSD11B1 (0.38) NPSR1KDM4EMAPTLMNAALDH1A1
SCHEMBL3191640 0.85 CYP3A4 (0.35) POLQNPSR1MAPTLMNAALDH1A1
SCHEMBL3183309 0.84 PSEN1 (0.44) POLQNPSR1MAPTLMNAALDH1A1
SCHEMBL3194619 0.83 ABCB11 (0.36) POLQMAPTLMNAALDH1A1HSD11B1
SCHEMBL3203126 0.82 NR3C1 (0.32) NPSR1KDM4EMAPTLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed