SCHEMBL3203596

SCHEMBL3203596

Cc1ccc(S(OS(=O)(=O)c2ccc(C(F)(F)F)cc2C(F)(F)F)(c2ccccc2)c2ccccc2)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.43
EPHX2 P34913 2/20 0.38
ALDH1A1 P00352 3/20 0.37
LMNA P02545 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MCOLN3 Q8TDD5 1/20 0.37
MAPT P10636 3/20 0.37
KDM4E B2RXH2 1/20 0.37
F2 P00734 1/20 0.37
POLB P06746 1/20 0.36
HPGD P15428 1/20 0.36
ALOX12 P18054 1/20 0.36
GFER P55789 1/20 0.36
ABCB11 O95342 1/20 0.36
HSD11B1 P28845 2/20 0.35
ABCC9 O60706 1/20 0.35
ABCC8 Q09428 1/20 0.35
KCNJ11 Q14654 1/20 0.35
KCNJ8 Q15842 1/20 0.35
CYP3A4 P08684 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3199737 0.89 CYP3A4 (0.42) MCL1ALDH1A1LMNAMCOLN3MAPT
SCHEMBL3201120 0.89 MCL1 (0.38) MCL1EPHX2ALDH1A1LMNASMN1; SMN2
SCHEMBL3201722 0.87 MCL1 (0.43) MCL1EPHX2ALDH1A1LMNASMN1; SMN2
SCHEMBL3189170 0.87 HSD11B1 (0.37) MCL1ALDH1A1LMNAMAPTKDM4E
SCHEMBL5403814 0.86 MCL1 (0.42) MCL1EPHX2ALDH1A1LMNAMCOLN3
SCHEMBL5408450 0.86 MCL1 (0.41) MCL1EPHX2ALDH1A1LMNASMN1; SMN2
SCHEMBL3202334 0.85 MCL1 (0.37) MCL1ALDH1A1LMNAMAPTKDM4E
SCHEMBL3191940 0.81 ALDH1A1 (0.40) MCL1ALDH1A1LMNAMAPTKDM4E
SCHEMBL3202138 0.81 POLQ (0.34) MCL1ALDH1A1LMNAMCOLN3MAPT
SCHEMBL3181645 0.81 ALDH1A1 (0.40) ALDH1A1KDM4EPOLBHPGDGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed