SCHEMBL3199797

SCHEMBL3199797

CNC(=O)c1cc(Cl)cc(Cl)c1NC(=O)c1cc(OS(C)(=O)=O)nn1-c1ncccc1Cl

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 3/20 0.34
NTRK1 P04629 5/20 0.32
RBP4 P02753 1/20 0.32
DHODH Q02127 2/20 0.32
EPHX2 P34913 1/20 0.32
KMT2A Q03164 1/20 0.31
CNR1 P21554 1/20 0.31
POLB P06746 1/20 0.31
ALB P02768 1/20 0.31
HTR1A P08908 1/20 0.31
SLC6A2 P23975 1/20 0.31
PDE4A P27815 1/20 0.31
OPRM1 P35372 1/20 0.31
DRD3 P35462 1/20 0.31
HTR2B P41595 1/20 0.31
SLC6A3 Q01959 1/20 0.31
PDE4D Q08499 1/20 0.31
SHH Q15465 1/20 0.31
USP28 Q96RU2 1/20 0.31
SLC29A1 Q99808 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3196343 0.92 CNR1 (0.33) RBP4DHODHKMT2ACNR1POLB
SCHEMBL782242 0.85 MALT1 (0.38) MALT1NTRK1RBP4DHODHEPHX2
SCHEMBL10028755 0.85 EPHX2 (0.38) MALT1NTRK1DHODHEPHX2POLB
SCHEMBL12528237 0.85 NTRK1 (0.39) MALT1NTRK1KMT2A
SCHEMBL782140 0.84 DHODH (0.42) MALT1NTRK1RBP4DHODHEPHX2
SCHEMBL12935676 0.84 MALT1 (0.37) MALT1NTRK1RBP4DHODHEPHX2
SCHEMBL21224045 0.83 MALT1 (0.36) MALT1RBP4DHODHEPHX2KMT2A
SCHEMBL28496160 0.83 MALT1 (0.33) MALT1NTRK1RBP4DHODHEPHX2
SCHEMBL782241 0.81 CARM1 (0.40) MALT1KMT2APOLB
SCHEMBL7128492 0.81 MALT1 (0.35) MALT1NTRK1DHODHALBHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1560820-B1 NOVEL ANTHRANILAMIDE INSECTICIDES DU PONT (US) 2010-05-26 EP disclosed
US-7666882-B2 1-(3-Chloro-2-pyridinyl)-N-[2,4-dichloro-6-[[(1-methylethyl)amino]carbonyl]phenyl]-3-(2-propynyloxy)-1H-pyrazole-5-carboxamide; controlling an invertebrate pest; less costly, less toxic, environmentally safer E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-02-23 US disclosed
US-20060014808-A1 Novel anthranilamide insecticides E. I. DU PONT DE NEMOURS AND COMPANY 2006-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060014808-A1 Novel anthranilamide insecticides RTN4, ANTXR2, SCN4A MALT1 3114/4885NTRK1 3411/4885RBP4 1386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.