SCHEMBL3199894

SCHEMBL3199894

O=C(O)CC(NC(=O)OCC1c2ccccc2-c2ccccc21)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 4/20 0.59
KMT2A Q03164 2/20 0.53
MDM4 O15151 1/20 0.48
TP53 P04637 1/20 0.48
EPHX2 P34913 1/20 0.48
FABP7 O15540 1/20 0.44
FABP5 Q01469 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29624364 1.00 CASP3 (0.59) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL3835254 1.00 CASP3 (0.59) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL31299005 1.00 CASP3 (0.59) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL3199882 1.00 CASP3 (0.59) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL26654416 0.99 CASP3 (0.58) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL26654411 0.99 CASP3 (0.58) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL5846051 0.93 CASP3 (0.55) CASP3KMT2AMDM4TP53
SCHEMBL3230119 0.92 CASP3 (0.54) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL7198189 0.92 CASP3 (0.54) CASP3KMT2AMDM4TP53EPHX2
SCHEMBL3725037 0.92 CASP3 (0.54) CASP3KMT2AMDM4TP53EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250368680-A1 METHOD FOR PRODUCING SALT OF AMINO ACID OR SALT OF PEPTIDE COMPOUND OR SOLVATE OF EITHER ONE OF SAID SALTS COMPRISING LITHIUM SALT PRECIPITATION STEP CHUGAI PHARMACEUTICAL CO LTD (JP) 2025-12-04 US disclosed
EP-4520748-A1 METHOD FOR PRODUCING SALT OF AMINO ACID OR SALT OF PEPTIDE COMPOUND OR SOLVATE OF EITHER ONE OF SAID SALTS COMPRISING LITHIUM SALT PRECIPITATION STEP CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-03-12 EP disclosed
WO-2023219152-A1 METHOD FOR PRODUCING SALT OF AMINO ACID OR SALT OF PEPTIDE COMPOUND OR SOLVATE OF EITHER ONE OF SAID SALTS COMPRISING LITHIUM SALT PRECIPITATION STEP 中外製薬株式会社 2023-11-16 WO disclosed
EP-3515880-B1 METHODS AND COMPOSITIONS FOR SYNTHESIS OF ENCODED LIBRARIES HITGEN INC (CN) 2023-05-10 EP disclosed
US-9682123-B2 Methods of treating metabolic disease THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2017-06-20 US disclosed
US-20150190466-A1 METHODS OF TREATING METABOLIC DISEASE NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2015-07-09 US disclosed
US-20130160150-A1 METHODS FOR IDENTIFYING COMPOUNDS THAT MODULATE LISCH-LIKE PROTEIN OR C1ORF32 PROTEIN ACTIVITY AND METHODS OF USE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2013-06-20 US disclosed
US-8460880-B2 Compositions, splice variants and methods relating to ovarian specific genes and proteins DIADEXUS, INC. (US) 2013-06-11 US disclosed
US-7678889-B2 Compositions and methods relating to ovarian specific genes and proteins DIADEXUS, INC. (US) 2010-03-16 US disclosed
US-20100029609-A1 BIARYL SULFONAMIDE DERIVATIVES NOVARTIS AG (CH) 2010-02-04 US disclosed
CN-1333755-A Benzimidazole compounds as vitronectin receptor antagonists SCHERING CORP (US) 2002-01-30 CN disclosed
WO-2001092524-A2 MYOSIN-LIKE GENE EXPRESSED IN HUMAN HEART AND MUSCLE AEOMICA, INC. (US) 2001-12-06 WO disclosed
EP-1135374-A1 BENZIMIDAZOLE COMPOUNDS THAT ARE VITRONECTIN RECEPTOR ANTAGONISTS SCHERING CORPORATION (US) 2001-09-26 EP disclosed
EP-1115724-A1 QUINOLIZINONES AS INTEGRIN INHIBITORS Shire Biochem Inc. (CA) 2001-07-18 EP disclosed
US-6204282-B1 TREATING CANCER, RETINOPATHY, ATHEROSCLEROSIS, VASCULAR RESTENOSIS, OR OSTEOPOROSIS. SCHERING CORPORATION 2001-03-20 US disclosed
EP-1021424-A1 THIADIAZOLE AMIDE MMP INHIBITORS PHARMACIA & UPJOHN COMPANY (US) 2000-07-26 EP disclosed
WO-2000032578-A1 BENZIMIDAZOLE COMPOUNDS THAT ARE VITRONECTIN RECEPTOR ANTAGONISTS SCHERING CORPORATION (US) 2000-06-08 WO disclosed
WO-2000017197-A1 QUINOLIZINONES AS INTEGRIN INHIBITORS BIOCHEM PHARMA INC. (US) 2000-03-30 WO disclosed
US-5830869-A METALLOPROTEASE INHIBITOR PHARMACIA & UPJOHN COMPANY 1998-11-03 US disclosed
WO-1997048688-A1 THIADIAZOLE AMIDE MMP INHIBITORS PHARMACIA & UPJOHN COMPANY (US) 1997-12-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250368680-A1 METHOD FOR PRODUCING SALT OF AMINO ACID OR SALT OF PEPTIDE COMPOUND OR SOLVATE OF EITHER ONE OF SAID SALTS COMPRISING LITHIUM SALT PRECIPITATION STEP NPPA, DNPEP, NPEPPS CASP3 2635/4885KMT2A 3331/4885MDM4 2388/4885
US-20100029609-A1 BIARYL SULFONAMIDE DERIVATIVES UGT2B7, CYP3A7, STS CASP3 104/4885KMT2A 2404/4885MDM4 4541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.