Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.68 |
| ▸ | CA1 | P00915 | 17/20 | 0.68 |
| ▸ | CA4 | P22748 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL11577501 | 0.97 | CA2 (0.65) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL28535771 | 0.97 | CA2 (0.65) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL26133489 | 0.97 | CA2 (0.65) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL11577494 | 0.97 | CA2 (0.65) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL9130683 | 0.97 | CA2 (0.65) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL1535442 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL2841686 | 0.93 | CA2 (0.78) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL166041 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL20704875 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR | |
| Terephthalic Acid SCHEMBL10900872 | 0.93 | CA2 (0.68) | CA2CA1CA4TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1093 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119639498-A | Composite calcium-based lubricating grease and preparation method thereof | 安徽中天石化股份有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-118977333-A | Stirring device and method for preparing low-Mooney white carbon black/natural latex composite material by adopting same | 青岛科技大学 | 2024-11-19 | — | — | CN | claimed |
| CN-118754339-A | Clean treatment method for alkali-reduction wastewater | 吉安市三菱超细纤维有限公司 | 2024-10-11 | — | — | CN | claimed |
| CN-115304867-B | Special resin for toughened PPR (Poly-p-phenylene-vinyl-copolymer) pipe and preparation method thereof | 中国石油天然气股份有限公司 | 2024-07-26 | — | — | CN | claimed |
| CN-118063859-A | Preparation method of high-dispersion nano silicon dioxide composite material | 扬州德鲁克科技有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-117700933-A | Calcium-based MOF material synergistic flame-retardant epoxy resin composite material and preparation method thereof | 常州大学 | 2024-03-15 | — | — | CN | claimed |
| CN-115257019-B | High-strength PET composite board and processing technology thereof | 江苏民扬塑胶科技有限公司 | 2023-10-31 | — | — | CN | claimed |
| CN-115304867-A | Special resin for toughened PPR (polypropylene random copolymer) pipe and preparation method thereof | 中国石油天然气股份有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-115257019-A | High-strength PET composite board and processing technology thereof | 江苏民扬塑胶科技有限公司 | 2022-11-01 | — | — | CN | claimed |
| CN-114479340-A | Composite plastic modified material | 常州市五洲环保科技有限公司 | 2022-05-13 | — | — | CN | claimed |
| WO-1994010690-A1 | ELECTRICAL INSULATING VINYL HALIDE RESIN COMPOSITIONS | SYNTHETIC PRODUCTS COMPANY (US) | 1994-05-11 | — | — | WO | claimed |
| EP-0567084-A1 | Polyester film for high density magnetic recording tape | DIAFOIL HOECHST CO., LTD (JP) | 1993-10-27 | — | — | EP | claimed |
| US-5164458-A | Metal carboxylate | SYNTHETIC PRODUCTS COMPANY (US) | 1992-11-17 | — | — | US | claimed |
| US-4983688-A | Liquid crystal polymer, polymeric polyvalent metal aromatic polycarboxylate, reinforcement | SYNTHETIC PRODUCTS COMPANY (US) | 1991-01-08 | — | — | US | claimed |
| WO-1990013596-A1 | HIGH PERFORMANCE ENGINEERING POLYMER COMPOSITIONS | SYNTHETIC PRODUCTS COMPANY (US) | 1990-11-15 | — | — | WO | claimed |
| US-4814426-A | TEREPHTHALIC ACID, CYCLOHEXANEDIMETHANOL BLEND | DIAFOIL COMPANY, LIMITED (JP) | 1989-03-21 | — | — | US | claimed |
| US-4198458-A | MAGNETIC TAPES | TEIJIN LIMITED (JP) | 1980-04-15 | — | — | US | claimed |
| US-4101523-A | POLYETHYLENE TEREPHTHALATE, CALCIUM TEREPHTHALATE ANHYDRIDE PARTICLES | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1978-07-18 | — | — | US | claimed |
| US-4096109-A | POLYETHYLENE TEREPHTHALATE, INERT PARTICLES | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1978-06-20 | — | — | US | claimed |
| US-4039515-A | TEREPHTHALIC ACID | BASF AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | claimed |