Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5401000 | 0.80 | LMNA (0.50) | CYP19A1TSHRMAPK1HIF1AMEN1 | |
| SCHEMBL10578903 | 0.79 | KCNN4 (0.35) | CYP19A1MAPK1 | |
| SCHEMBL320071 | 0.77 | ESR1 (0.48) | TSHRHIF1AMEN1KMT2ALMNA | |
| SCHEMBL10821951 | 0.77 | TRPV4 (0.31) | — | |
| SCHEMBL6516942 | 0.77 | CA1 (0.41) | CYP2A6 | |
| SCHEMBL3146868 | 0.77 | KIF11 (0.46) | TSHRMAPK1MEN1KMT2ALMNA | |
| SCHEMBL7870012 | 0.76 | TSHR (0.48) | TSHRMAPK1MEN1KMT2ALMNA | |
| SCHEMBL5238555 | 0.75 | CYP19A1 (0.45) | CYP19A1TSHRMAPK1HIF1AMEN1 | |
| SCHEMBL6864521 | 0.75 | ALDH1A1 (0.38) | CYP19A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL16626263 | 0.73 | CYP19A1 (0.50) | CYP19A1TSHRMAPK1HIF1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603182-B1 | Membrane electrode assembly and polymer electrolyte fuel cell comprising the same | HONDA MOTOR CO LTD (JP) | 2008-09-10 | — | — | EP | disclosed |
| EP-1603182-A1 | Membrane electrode assembly and polymer electrolyte fuel cell comprising the same | HONDA MOTOR CO., Ltd. (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-6515101-B1 | A polymer essentially of units of aromatic-based compounds, at least one of said aromatic-based compounds being substituted with at least one CF3 group, wherein said units are in the backbone of said polymer and do not contain elements other | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2003-02-04 | — | — | US | disclosed |