Naphthalene

Naphthalene

SCHEMBL3201055

O=S(=O)(O)N(S(=O)(=O)O)S(=O)(=O)O.c1ccc2ccccc2c1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX12 P18054 2/20 0.44
CYP2A6 P11509 1/20 0.44
TSHR P16473 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
LMNA P02545 1/20 0.38
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
CA1 P00915 3/20 0.35
CA2 P00918 3/20 0.35
CA9 Q16790 2/20 0.35
F2 P00734 1/20 0.35
PRSS1 P07477 1/20 0.35
PRSS2 P07478 1/20 0.35
PRSS3 P35030 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL28674544 0.82 ALOX12 (0.57) ALOX12CYP2A6TSHRSMN1; SMN2LMNA
Naphthalene SCHEMBL672294 0.82 ALOX12 (0.57) ALOX12CYP2A6TSHRSMN1; SMN2LMNA
Naphthalene SCHEMBL2678900 0.82 ALOX12 (0.57) ALOX12CYP2A6TSHRSMN1; SMN2LMNA
Naphthalene SCHEMBL5574575 0.82 ALOX12 (0.57) ALOX12CYP2A6TSHRSMN1; SMN2LMNA
Naphthalene SCHEMBL29361795 0.82 ALOX12 (0.57) ALOX12CYP2A6TSHRSMN1; SMN2LMNA
Naphthalene SCHEMBL5067412 0.81 CYP2A6 (0.42) ALOX12CYP2A6TSHRSMN1; SMN2LMNA
Naphthalene SCHEMBL9484717 0.79 ALOX12 (0.53) ALOX12CYP2A6TSHRSMN1; SMN2LMNA
Naphthalene SCHEMBL8773082 0.79 ALOX12 (0.53) ALOX12CYP2A6TSHRSMN1; SMN2LMNA
Naphthalene SCHEMBL28983768 0.79 ALOX12 (0.53) ALOX12CYP2A6TSHRSMN1; SMN2LMNA
Naphthalene SCHEMBL9484719 0.79 ALOX12 (0.53) ALOX12CYP2A6TSHRSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4652621-A MALEIMIDE WITH SULFONATE OR SULFATE GROUP, DRILLING FLUID DISPERSANT NIPPON ZEON CO., LTD. (JP) 1987-03-24 US claimed
EP-0138755-B1 PROCESS FOR THE ISOLATION OF 2-NAPHTHYLAMINE-3,6,8-TRISULPHONIC ACID AS MONOPOTASSIUM OR MONOAMMONIUM SALT CIBA-GEIGY AG (CH) 1987-02-04 EP claimed
US-4609503-A HYDROXYLATION BAYER AKTIENGESSELSCHAFT (DE) 1986-09-02 US claimed
US-4551283-A SULFONATION, SALT FORMATION, DISPERSANTS CIBA GEIGY AG (CH) 1985-11-05 US claimed
EP-2123724-B1 AQUEOUS INK COMPOSITION FOR BALLPOINT PEN PILOT INK CO LTD (JP) 2018-05-23 EP disclosed
US-8764333-B2 Water based ink compositions for ballpoint pen THE PILOT INK CO., LTD. (JP) 2014-07-01 US disclosed
US-8476369-B2 Metal salt nanogel-containing polymers BAYER INNOVATION GMBH (DE) 2013-07-02 US disclosed
US-20100178270-A1 METAL SALT NANOGEL-CONTAINING POLYMERS HELLING INNOVATION UG 2010-07-15 US disclosed
US-20100040401-A1 Water Based Ink Compositions For Ballpoint Pen THE PILOT INK CO., LTD. (JP) 2010-02-18 US disclosed
EP-2123724-A1 AQUEOUS INK COMPOSITION FOR BALLPOINT PEN THE PILOT INK CO., LTD. (JP) 2009-11-25 EP disclosed
EP-1704928-B1 Aqueous coating compositions DU PONT (US) 2008-05-28 EP disclosed
WO-2008043853-A2 PHOTOCHROMIC FILM OPCO GMBH (DE) 2008-04-17 WO disclosed
US-4426333-A Process for the preparation of 1-benzoylamino-8-hydroxynaphthalene-4,6-disulphonic acid (benzoyl-K acid) BAYER AKTIENGESELLSCHAFT (DE) 1984-01-17 US disclosed
US-4426334-A MIXED ALKALI SALTS, PRECIPITATION BAYER AKTIENGESELLSCHAFT (DE) 1984-01-17 US disclosed
US-4325889-A Process for the preparation of 1-amino-8-naphthol-3,6-disulphonic acid (H-acid) BAYER AKTIENGESELLSCHAFT (DE) 1982-04-20 US disclosed
US-4178308-A Process for the preparation of 1-amino-8-naphthol-3,6-disulphonic acid (H-acid) BAYER AKTIENGESELLSCHAFT (DE) 1979-12-11 US disclosed
US-4166826-A Process for the preparation of 1-amino-8-naphthol-3,6-disulphonic acid (H-acid) BAYER AKTIENGESELLSCHAFT (DE) 1979-09-04 US disclosed
US-4147801-A UREYLENEBIS/METHYL-PHENYLENE/UREYLENE//DI-1,3,6-NAPHTHALENE TRISULFONIC ACID AMERICAN CYANAMID COMPANY (US) 1979-04-03 US disclosed
US-4146640-A SULFONIC ACID AND SECONDARY AMIDE FUNCTIONAL GROUPS AMERICAN CYANAMID COMPANY (US) 1979-03-27 US disclosed
US-4087548-A NAPHTHALENE TRISULFONIC ACIDS AMERICAN CYANAMID COMPANY (US) 1978-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100178270-A1 METAL SALT NANOGEL-CONTAINING POLYMERS PUF60, WASHC5, SLC39A3 ALOX12 4037/4885CYP2A6 4491/4885TSHR 4678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.