Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL27184952 | 0.82 | ALDH1A1 (0.45) | SMN1; SMN2TSHRALDH1A1 | |
| Naphthalene SCHEMBL3201055 | 0.81 | ALOX12 (0.44) | CYP2A6ALOX12NPC1RAB9ASMN1; SMN2 | |
| Naphthalene SCHEMBL476327 | 0.80 | ALOX12 (0.50) | CYP2A6ALOX12SMN1; SMN2TSHRLMNA | |
| Benzene SCHEMBL8509063 | 0.80 | CA2 (0.38) | SMN1; SMN2TSHRLMNAHTTHSD11B1 | |
| Naphthalene SCHEMBL29361795 | 0.80 | ALOX12 (0.57) | CYP2A6ALOX12SMN1; SMN2TSHRLMNA | |
| Benzene SCHEMBL29962016 | 0.80 | CA2 (0.38) | SMN1; SMN2TSHRLMNAHTTHSD11B1 | |
| Naphthalene SCHEMBL5574575 | 0.80 | ALOX12 (0.57) | CYP2A6ALOX12SMN1; SMN2TSHRLMNA | |
| Naphthalene SCHEMBL672294 | 0.80 | ALOX12 (0.57) | CYP2A6ALOX12SMN1; SMN2TSHRLMNA | |
| Naphthalene SCHEMBL28674544 | 0.80 | ALOX12 (0.57) | CYP2A6ALOX12SMN1; SMN2TSHRLMNA | |
| Naphthalene SCHEMBL2678900 | 0.80 | ALOX12 (0.57) | CYP2A6ALOX12SMN1; SMN2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080177059-A1 | FREE CHOLESTEROL ANALOGS BEARING A BORON DIPYRROMETHENE DIFLUORO (BODIPY) FLUOROPHORE IN THE SIDE CHAIN AND METHOD OF PREPARATION AND USE THEREOF | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080177059-A1 | FREE CHOLESTEROL ANALOGS BEARING A BORON DIPYRROMETHENE DIFLUORO (BODIPY) FLUOROPHORE IN THE SIDE CHAIN AND METHOD OF PREPARATION AND USE THEREOF | NPC1L1, CETP, NPC1 | CYP2A6 1236/4885ALOX12 3722/4885NPC1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.