Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 4/20 | 0.80 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5087658 | 1.00 | SLC22A1 (0.80) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL5091328 | 1.00 | SLC22A1 (0.80) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL11826400 | 0.97 | SLC22A1 (0.75) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| SCHEMBL2870319 | 0.97 | SLC22A1 (0.86) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| SCHEMBL2870114 | 0.97 | SLC22A1 (0.86) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| SCHEMBL1684241 | 0.97 | SLC22A1 (0.86) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Tetrabuthylammonium SCHEMBL2522406 | 0.97 | SLC22A1 (0.86) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL5087066 | 0.93 | SLC22A1 (0.80) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Water SCHEMBL3308155 | 0.93 | SLC22A1 (0.80) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL5087568 | 0.93 | SLC22A1 (0.80) | SLC22A1SLC22A2ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685274-A | Esterification method for preparing 4-methyl chloroacetoacetate | 江西迪赛诺制药有限公司 | 2022-07-01 | — | — | CN | claimed |
| EP-4282522-A1 | SILICA-SUPPORTED IONIC LIQUIDS FOR THE REMOVAL OF CYTOSTATICS FROM AQUEOUS SAMPLES | Universidade de Aveiro (PT) | 2023-11-29 | — | — | EP | disclosed |
| CN-114685274-A | Esterification method for preparing 4-methyl chloroacetoacetate | 江西迪赛诺制药有限公司 | 2022-07-01 | — | — | CN | disclosed |
| US-10823477-B2 | Thermal energy storage member and storage container using the same, and refrigerator using the same | SHARP KABUSHIKI KAISHA (JP) | 2020-11-03 | — | — | US | disclosed |
| CN-105452261-B | continuous process for preparing thiocarboxylate silane | 莫门蒂夫性能材料股份有限公司 | 2019-12-10 | — | — | CN | disclosed |
| EP-3019507-B1 | CONTINUOUS PROCESS FOR THE PREPARATION OF THIOCARBOXYLATE SILANE | MOMENTIVE PERFORMANCE MAT INC (US) | 2017-06-21 | — | — | EP | disclosed |
| US-20160370084-A1 | THERMAL ENERGY STORAGE MEMBER AND STORAGE CONTAINER USING THE SAME, AND REFRIGERATOR USING THE SAME | SHARP KABUSHIKI KAISHA (JP) | 2016-12-22 | — | — | US | disclosed |
| EP-3019507-A1 | CONTINUOUS PROCESS FOR THE PREPARATION OF THIOCARBOXYLATE SILANE | Momentive Performance Materials Inc. (US) | 2016-05-18 | — | — | EP | disclosed |
| US-9193742-B2 | Continuous process for the preparation of thiocarboxylate silane | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2015-11-24 | — | — | US | disclosed |
| US-20150080595-A1 | CONTINUOUS PROCESS FOR THE PREPARATION OF THIOCARBOXYLATE SILANE | MOMENTIVE PERFORMANCE MATERIALS INC. | 2015-03-19 | — | — | US | disclosed |
| US-20050270350-A1 | Chemically-modified coatings for enhanced performance of ink-jet images | VINCENT KENT D | 2005-12-08 | — | — | US | disclosed |
| US-6951672-B2 | Chemically-modified coatings for enhanced performance of ink-jet images | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2005-10-04 | — | — | US | disclosed |
| EP-1502760-A1 | Ink-jet recording method using chemically-modified pigment coatings | Hewlett-Packard Development Company, L.P. (US) | 2005-02-02 | — | — | EP | disclosed |
| US-20040219311-A1 | Chemically-bonded porous coatings that enhance humid fastness and fade fastness performance of ink jet images | WICKRAMANAYAKE PALITHA (US) | 2004-11-04 | — | — | US | disclosed |
| US-20030175451-A1 | Chemically-bonded porous coatings that enhance humid fastness and fade fastness performance of ink jet images | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2003-09-18 | — | — | US | disclosed |
| EP-1344654-A1 | Printing substrate comprising a coating of organo silane modified silica | Hewlett-Packard Company (US) | 2003-09-17 | — | — | EP | disclosed |
| US-5814226-A | Method of removing heavy metal ions from a liquid with chemically active ceramic compositions with a thiol and/or amine moiety | SYRACUSE UNIVERSITY (US) | 1998-09-29 | — | — | US | disclosed |
| US-5616533-A | Chemically active ceramic compositions with a thiol and/or amine moiety | SYRACUSE UNIVERSITY (US) | 1997-04-01 | — | — | US | disclosed |
| US-4009116-A | Process of preparing substantially organic waste liquids containing radioactive or toxic substances for safe, non-pollutive handling, transportation and permanent storage | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-22 | — | — | US | disclosed |
| US-3960762-A | Production of absorbents | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150080595-A1 | CONTINUOUS PROCESS FOR THE PREPARATION OF THIOCARBOXYLATE SILANE | TST, CTH, STS | SLC22A1 1040/4885SLC22A2 1171/4885ALDH1A1 249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.