Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR6 | O00574 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13490703 | 0.94 | CXCR6 (0.49) | CXCR6NPC1POLBRAB9AKMT2A | |
| Trifluoroacetic Acid SCHEMBL3199468 | 0.86 | NPC1 (0.45) | CXCR6NPC1RAB9AKMT2AMEN1 | |
| Trifluoroacetic Acid SCHEMBL3224483 | 0.84 | MLLT1 (0.47) | KMT2ASETD2 | |
| Trifluoroacetic Acid SCHEMBL3205981 | 0.82 | LMNA (0.43) | — | |
| Trifluoroacetic Acid SCHEMBL3226942 | 0.80 | CXCR6 (0.48) | CXCR6HTR2B | |
| Trifluoroacetic Acid SCHEMBL3215410 | 0.80 | CXCR6 (0.48) | CXCR6HTR2B | |
| Trifluoroacetic Acid SCHEMBL3210802 | 0.80 | RAB9A (0.55) | CXCR6NPC1RAB9AKMT2AMEN1 | |
| Trifluoroacetic Acid SCHEMBL3210512 | 0.80 | HTR2B (0.43) | CXCR6HTR2B | |
| Trifluoroacetic Acid SCHEMBL3210746 | 0.80 | SMN1; SMN2 (0.47) | POLBRAB9AKMT2A | |
| SCHEMBL13490706 | 0.80 | SMN1; SMN2 (0.47) | CXCR6NPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | ACIN1, HAT1, CCNE1 | CXCR6 3847/4885NPC1 3250/4885POLB 3043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.