SCHEMBL3203042

SCHEMBL3203042

CCCCC(=N)c1ccccc1C1c2ccccc2-c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.41
BCHE P06276 1/20 0.41
LTB4R2 Q9NPC1 5/20 0.36
HTR2A P28223 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
CHRM2 P08172 2/20 0.34
ADRA2A P08913 2/20 0.34
SLC6A3 Q01959 2/20 0.34
KDM4E B2RXH2 1/20 0.34
RECQL P46063 1/20 0.34
NR1I2 O75469 1/20 0.34
LMNA P02545 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 1/20 0.34
OPRK1 P41145 1/20 0.34
HTR2B P41595 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
PTGS2 P35354 1/20 0.33
TSHR P16473 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3190456 0.84 BCHE (0.37) ACHEBCHELTB4R2HTR2ALMNA
SCHEMBL3202608 0.83 SLC10A2 (0.36) ACHEBCHELTB4R2HTR1A
SCHEMBL3206046 0.79 CYP3A4 (0.33) MEN1KMT2ACHRM2ADRA2ASLC6A3
SCHEMBL3202527 0.79 BCHE (0.37) ACHEBCHEMEN1KMT2AKDM4E
SCHEMBL3203901 0.76 MEN1 (0.34) LTB4R2MEN1KMT2ACHRM2ADRA2A
SCHEMBL3215797 0.75 SIGMAR1 (0.33) HTR2AMEN1KMT2ACHRM2SLC6A3
SCHEMBL17559474 0.71 MEN1 (0.38) MEN1KMT2ACHRM2ADRA2ASLC6A3
SCHEMBL3201092 0.70 GPR3 (0.34) ACHEBCHEHTR2AKMT2ASLC6A3
SCHEMBL3198973 0.70 LTB4R2 (0.35) LTB4R2MEN1KMT2AKDM4ERECQL
SCHEMBL3213582 0.69 PTGS2 (0.32) LTB4R2MEN1KMT2AKDM4ERECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed