Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.32 |
| ▸ | GSTM2 | P28161 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 3/20 | 0.31 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 5/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | CTSB | P07858 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5059455 | 0.80 | TDP1 (0.46) | TDP1IDO1ALDH1A1HIF1AMAPT | |
| SCHEMBL31589258 | 0.80 | ALDH1A1 (0.40) | TDP1ALDH1A1MAPTGSTP1GSTM2 | |
| SCHEMBL1752719 | 0.80 | GPR35 (0.44) | TDP1IDO1ALDH1A1HIF1AMAPT | |
| SCHEMBL3183167 | 0.77 | MEN1 (0.34) | TDP1ATMALDH1A1HIF1AMAPT | |
| SCHEMBL29732491 | 0.76 | MEN1 (0.46) | TDP1ALDH1A1MAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL19244 | 0.76 | MEN1 (0.46) | TDP1ALDH1A1MAPTSMN1; SMN2CYP3A4 | |
| Fluoride SCHEMBL10627364 | 0.75 | MEN1 (0.45) | TDP1ALDH1A1MAPTSMN1; SMN2CYP3A4 | |
| Hydrochloric Acid SCHEMBL10625153 | 0.75 | MEN1 (0.45) | TDP1ALDH1A1MAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL3203718 | 0.73 | TDP1 (0.41) | TDP1ATMIDO1ALDH1A1HIF1A | |
| SCHEMBL2333611 | 0.73 | TDP1 (0.41) | TDP1ATMIDO1ALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029013-A1 | Methods for Detecting Asymmetric Dimethylarginine in a Biological Sample | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-02-04 | — | — | US | disclosed |
| US-7611844-B2 | Methods for detecting asymmetric dimethylarginine in a biological sample | BOARD OF TRUSTEES OF THE LELAND STANFORD JR. UNIVERSITY (US) | 2009-11-03 | — | — | US | disclosed |
| US-20040214252-A1 | Methods for detecting asymmetric dimethylarginine in a biological sample | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-10-28 | — | — | US | disclosed |
| WO-2004046314-A2 | METHODS FOR DETECTING ASYMMETRIC DIMETHYLARGININE IN A BIOLOGICAL SAMPLE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2004-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029013-A1 | Methods for Detecting Asymmetric Dimethylarginine in a Biological Sample | ADM2, PADI3, PADI4 | TDP1 623/4885ATM 1529/4885IDO1 228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.