SCHEMBL3203856

SCHEMBL3203856

CC(C)(C)Oc1ccc([S+](c2ccccc2)c2ccccc2)c(OC(C)(C)C)c1.O=S(=O)([O-])c1ccc(C(F)(F)F)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.34
LMNA P02545 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
HTT P42858 2/20 0.34
NR3C1 P04150 1/20 0.33
PGR P06401 1/20 0.33
ESR2 Q92731 1/20 0.33
PTGDR2 Q9Y5Y4 3/20 0.33
AVPR2 P30518 1/20 0.32
GPR27 Q9NS67 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
ALOX15 P16050 1/20 0.32
MAPK1 P28482 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
CCR1 P32246 1/20 0.32
CCR2 P41597 1/20 0.32
HSD11B1 P28845 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3194611 0.90 HSD11B1 (0.33) ARLMNASMN1; SMN2NR3C1PGR
SCHEMBL3194018 0.89 FFAR1 (0.34) ARLMNASMN1; SMN2HTTNR3C1
SCHEMBL3181675 0.88 HSD11B1 (0.31) HSD11B1
SCHEMBL3200897 0.87 PTGDR2 (0.36) ARNR3C1PGRESR2PTGDR2
SCHEMBL3182699 0.86 HSD11B1 (0.33) HSD11B1
SCHEMBL2902275 0.85 AR (0.39) ARLMNASMN1; SMN2HTTNR3C1
SCHEMBL3195811 0.83 SLC6A9 (0.30)
SCHEMBL3190556 0.83 AR (0.35) ARLMNASMN1; SMN2HTTNR3C1
SCHEMBL3193889 0.83 PKM (0.31) SMN1; SMN2KMT2AMAPK1
SCHEMBL3182794 0.82 KIF11 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7060414-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-06-13 US disclosed
US-20050158657-A1 Radiation-sensitive resin composition SUZUKI AKI (JP) 2005-07-21 US disclosed
US-6899989-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2005-05-31 US disclosed