Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.62 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16742711 | 0.90 | TDP1 (0.60) | TDP1TSHRCYP2C19PTGDR2KDM4E | |
| SCHEMBL320418 | 0.87 | PTGDR2 (0.66) | TDP1TSHRCYP2C19PTGDR2KDM4E | |
| SCHEMBL15445592 | 0.83 | TSHR (0.71) | TDP1TSHRCYP2C19MRGPRX4PPARG | |
| SCHEMBL10359783 | 0.83 | PPARG (0.67) | TDP1TSHRCYP2C19PTGDR2MRGPRX4 | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL23242752 | 0.83 | TDP1 (0.93) | TDP1TSHRCYP2C19PTGDR2MAPT | |
| SCHEMBL17269686 | 0.83 | POLB (0.64) | TDP1TSHRCYP2C19PTGDR2KDM4E | |
| SCHEMBL5275178 | 0.83 | POLB (0.64) | TDP1TSHRCYP2C19PTGDR2KDM4E | |
| SCHEMBL3203787 | 0.83 | TDP1 (0.70) | TDP1TSHRCYP2C19PTGDR2PPARD | |
| SCHEMBL2113005 | 0.82 | PTGDR2 (0.64) | TDP1TSHRPTGDR2MRGPRX4PPARG | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL27783 | 0.82 | TDP1 (1.00) | TDP1TSHRCYP2C19PTGDR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200107547-A1 | Carbamoyl Triazolinone Based Herbicide Combinations and Method of Use | ARYSTA LIFESCIENCE CORP (JP) | 2020-04-09 | — | — | US | claimed |
| CN-101027279-B | Synthesis of tetracyclines and analogues thereof | HARVARD COLLEGE | 2013-03-27 | — | — | CN | claimed |
| WO-2010143071-A2 | CARBAMOYL TRIAZOLINONE BASED HERBICIDE COMBINATIONS AND METHODS OF USE | ARYSTA LIFESCIENCE CORPORATION (JP) | 2010-12-16 | — | — | WO | claimed |
| US-20100311589-A1 | CARBAMOYL TRIAZOLINONE BASED HERBICIDE COMBINATIONS AND METHOD OF USE | ARYSTA LIFESCIENCE CORPORATION (JP) | 2010-12-09 | — | — | US | claimed |
| US-20100184599-A1 | HERBICIDE COMPOSITION COMPRISING HERBICIDE COMPOUND IN ACID FORM AND ACIDIFYING AGENT | PLATTE CHEMICAL COMPANY (US) | 2010-07-22 | — | — | US | claimed |
| JP-58164501-A | — | — | None | — | — | JP | disclosed |
| JP-58057303-A | — | — | None | — | — | JP | disclosed |
| CN-117751114-A | Small molecule modulators of glucocerebrosidase activity and uses thereof | 凡况生化公司 | 2024-03-22 | — | — | CN | disclosed |
| US-11917994-B2 | Carbamoyl triazolinone based herbicide combinations and method of use | ARYSTA LIFESCIENCE CORPORATION (JP) | 2024-03-05 | — | — | US | disclosed |
| CN-117642404-A | Small molecule modulators of glucocerebrosidase activity and uses thereof | 凡况生化公司 | 2024-03-01 | — | — | CN | disclosed |
| US-20230165815-A1 | ROLES OF MODULATORS OF INTERSECTIN-CDC42 SIGNALING IN ALZHEIMER?S DISEASE | Lu, Qun (US) | 2023-06-01 | — | — | US | disclosed |
| US-20220378047-A1 | CARBAMOYL TRIAZOLINONE BASED HERBICIDE COMBINATIONS AND METHODS OF USE | ARYSTA LIFESCIENCE CORP (JP) | 2022-12-01 | — | — | US | disclosed |
| US-4261729-A | Herbicidal compositions and pyrazole derivatives | SANKYO COMPANY LIMITED (JP) | 1981-04-14 | — | — | US | disclosed |
| US-4146726-A | HERBICIDES | SANKYO COMPANY LIMITED (JP) | 1979-03-27 | — | — | US | disclosed |
| US-4063925-A | Herbicidal compositions | SANKYO COMPANY LIMITED (JA) | 1977-12-20 | — | — | US | disclosed |
| US-4060402-A | HERBICIDE | SANKYO COMPANY LIMITED (JA) | 1977-11-29 | — | — | US | disclosed |
| US-4052395-A | AGRICULTURAL FUNGICIDAL COMPOSITIONS CONTAINING 6-(SUBSTITUTED PHENYL)-PYRIDAZINONES AND SAID PYRIDAZINONES | SANKYO COMPANY LIMITED (JA) | 1977-10-04 | — | — | US | disclosed |
| US-4044018-A | Isoxazolone derivatives, their preparation and their use as plant growth regulators | SANKYO COMPANY LIMITED (JA) | 1977-08-23 | — | — | US | disclosed |
| US-4036631-A | Pyrazolone derivatives and their use as herbicides | SANKYO COMPANY LIMITED (JA) | 1977-07-19 | — | — | US | disclosed |
| US-3940260-A | TRICHLOROACETIC ACID, ESTERS OR SALTS AND 2,4-DICHLORO- OR 2,4,5-TRICHLORO- PHENOXYACETIC ACID, ESTERS OR SALTS | AMCHEM PRODUCTS, INC. (US) | 1976-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184599-A1 | HERBICIDE COMPOSITION COMPRISING HERBICIDE COMPOUND IN ACID FORM AND ACIDIFYING AGENT | DDT, CA3, DNPH1 | TDP1 2589/4885TSHR 2534/4885CYP2C19 658/4885 |
| US-11917994-B2 | Carbamoyl triazolinone based herbicide combinations and method of use | DDT, NOTUM, WEE1 | TDP1 2192/4885TSHR 1520/4885CYP2C19 453/4885 |
| US-20220378047-A1 | CARBAMOYL TRIAZOLINONE BASED HERBICIDE COMBINATIONS AND METHODS OF USE | DDT, NOTUM, WEE1 | TDP1 2074/4885TSHR 1534/4885CYP2C19 626/4885 |
| US-20200107547-A1 | Carbamoyl Triazolinone Based Herbicide Combinations and Method of Use | DDT, NOTUM, WEE1 | TDP1 2192/4885TSHR 1520/4885CYP2C19 453/4885 |
| US-20230165815-A1 | ROLES OF MODULATORS OF INTERSECTIN-CDC42 SIGNALING IN ALZHEIMER?S DISEASE | CDC42, MDN1, GAP43 | TDP1 1980/4885TSHR 3939/4885CYP2C19 4585/4885 |
| US-20100311589-A1 | CARBAMOYL TRIAZOLINONE BASED HERBICIDE COMBINATIONS AND METHOD OF USE | DDT, NOTUM, WEE1 | TDP1 2192/4885TSHR 1520/4885CYP2C19 453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.