Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.61 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.60 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 5/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765038 | 0.86 | PTGDR2 (0.56) | FFAR1PTGDR2PKMKDM4E | |
| SCHEMBL12667947 | 0.85 | FFAR1 (0.60) | FFAR1PTGDR2MRGPRX4PPARDPPARG | |
| SCHEMBL320418 | 0.84 | PTGDR2 (0.66) | FFAR1PTGDR2PKMKDM4E | |
| SCHEMBL14066214 | 0.83 | PTGDR2 (0.60) | PTGDR2PKMKDM4E | |
| SCHEMBL2113005 | 0.82 | PTGDR2 (0.64) | PTGDR2MRGPRX4KDM4EPPARDPPARG | |
| SCHEMBL2949180 | 0.82 | PKM (0.70) | FFAR1PTGDR2PKMPPARDPPARG | |
| SCHEMBL29951797 | 0.81 | PTGDR2 (0.69) | PTGDR2KDM4E | |
| SCHEMBL2717225 | 0.81 | PTGDR2 (0.62) | FFAR1PTGDR2PKMKDM4E | |
| SCHEMBL14273072 | 0.80 | PTGDR2 (0.57) | FFAR1PTGDR2PKMKDM4E | |
| SCHEMBL5533467 | 0.80 | FFAR1 (0.52) | FFAR1PTGDR2PKMPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306520-A1 | THIOPHENE COMPOUND AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2024-01-17 | — | — | EP | disclosed |
| US-8198458-B2 | Non-nucleoside reverse transcriptase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-12 | — | — | US | disclosed |
| US-7517998-B2 | Benzothiazole or benzothiazine derivative of dipyrido(2,3;b:2',3'-e) diazepin-6-one; viricide against human t-cell leukemia/lymphoma virus | BOEHRINGER INGELHEIM INTERNATIONAL GMBH | 2009-04-14 | — | — | US | disclosed |