SCHEMBL320438

SCHEMBL320438

COC(=O)N1C(=O)C=CC1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX4 Q99571 2/20 0.48
BCHE P06276 1/20 0.42
MGLL Q99685 4/20 0.38
ALDH1A1 P00352 3/20 0.38
GSK3A P49840 2/20 0.38
GSK3B P49841 2/20 0.38
BLM P54132 2/20 0.38
HPGD P15428 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C19 P33261 1/20 0.38
WRN Q14191 1/20 0.38
HIF1A Q16665 1/20 0.38
LPO P22079 4/20 0.36
NPSR1 Q6W5P4 2/20 0.33
GMNN O75496 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
THPO P40225 1/20 0.33
PMP22 Q01453 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3630207 1.00 P2RX4 (0.48) P2RX4BCHEMGLLALDH1A1GSK3A
Propionic Acid SCHEMBL28919819 0.88 ALDH1A1 (0.43) P2RX4BCHEMGLLALDH1A1GSK3A
SCHEMBL13674056 0.85 P2RX4 (0.42) P2RX4BCHEMGLLALDH1A1GSK3A
SCHEMBL2105111 0.78 P2RX4 (0.40) P2RX4BCHELPOPSEN1PSEN2
SCHEMBL1678307 0.76 GSK3A (0.57) BCHEMGLLALDH1A1GSK3AGSK3B
SCHEMBL19479170 0.75 ALDH1A1 (0.33) MGLLALDH1A1GSK3AGSK3BBLM
SCHEMBL8014569 0.75 BCHE (0.47) BCHEMGLLALDH1A1BLMHPGD
SCHEMBL4463617 0.73 ALDH1A1 (0.39) P2RX4MGLLALDH1A1GSK3AGSK3B
SCHEMBL9642610 0.72 P2RX4 (0.34) P2RX4BCHEMGLLALDH1A1GSK3A
SCHEMBL18485436 0.72 ALDH1A1 (0.44) BCHEMGLLALDH1A1GSK3AGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1473 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059920-A Dioxetane chemiluminescent probe suitable for bio-orthogonal catalytic reaction and synthesis and application thereof 华南理工大学 2026-05-19 CN claimed
CN-120005123-A Acrylic ester block copolymer resin, photoresist, and preparation method and application thereof 中国石油化工股份有限公司 2025-05-16 CN claimed
CN-119930866-A Catalyst component containing pyrroline compound, preparation method thereof, olefin polymerization catalyst, olefin polymerization method and olefin polymer 中国石油化工股份有限公司 2025-05-06 CN claimed
CN-118526608-A Nanometer medicine for preventing and/or treating retinoblastoma and preparation method and application thereof 中山大学附属第五医院 2024-08-23 CN claimed
CN-117647913-A Negative photosensitive resin composition, application thereof, hardening film, preparation thereof and electronic device 深圳市道尔顿电子材料股份有限公司 2024-03-05 CN claimed
CN-116904143-A Room-temperature-cured temperature-resistant PMMA adhesive and manufacturing method thereof 浙江华帅特新材料科技有限公司 2023-10-20 CN claimed
EP-3552023-B1 MAPPING PROTEIN BINDING SITES AND CONFORMATIONAL EPITOPES USING CYSTEINE LABELLING AND SURFACE DISPLAY LIBRARY INDIAN INST SCIENT (IN) 2022-04-27 EP claimed
US-11221339-B2 Mapping protein binding sites and conformational epitopes using cysteine labelling and surface display library INDIAN INSTITUTE OF SCIENCE (IN) 2022-01-11 US claimed
CN-109432449-B Iron complex MRI contrast agent and preparation method and application thereof 华南师范大学 2021-07-30 CN claimed
US-20200399428-A1 SYSTEMS, METHODS AND HYDROGELS FOR CELL CULTURE AND ANALYSIS PHENOMEX INC. (US) 2020-12-24 US claimed
CN-1271115-C Poly glycol long chain fatty alkyl maleimide derivative and its medicinal combination JIANKAI SCIENCE AND TECHNOLOGY (CN) 2006-08-23 CN claimed
JP-2006512445-A 2006-04-13 JP claimed
CN-1732206-A Hydrolytically stable maleimide-terminated polymers NEKTAR THERAPEUTICS AL CORP (US) 2006-02-08 CN claimed
US-20050249662-A1 Marked maleimide compounds, method for preparing same and use thereof for marking macromolecules COMMISSARIAT A L'ENERGIE (FR) 2005-11-10 US claimed
EP-1578842-A2 HYDROLYTICALLY STABLE MALEIMIDE-TERMINATED POLYMERS Nektar Therapeutics Al, Corporation (US) 2005-09-28 EP claimed
EP-1517903-A2 MARKED MALEIMIDE COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR MARKING MACROMOLECULES COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2005-03-30 EP claimed
US-20040204548-A1 Hydrolytically stable maleimide-terminated polymers NEKTAR THERAPEUTICS 2004-10-14 US claimed
WO-2004060965-A2 HYDROLYTICALLY STABLE MALEIMIDE-TERMINATED POLYMERS NEKTAR THERAPEUTICS AL, CORPORATION (US) 2004-07-22 WO claimed
CN-1511860-A Poly glycol long chain fatty alkyl maleimide derivative and its medicinal combination 北京键凯科技有限公司 2004-07-14 CN claimed
WO-2004002984-A2 MARKED MALEIMIDE COMPOUNDS, METHOD FOR PREPARING SAME AND USE THEREOF FOR MARKING MACROMOLECULES COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2004-01-08 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050249662-A1 Marked maleimide compounds, method for preparing same and use thereof for marking macromolecules CRBN, NR2E3, NR2C2 P2RX4 1558/4885BCHE 2340/4885MGLL 4532/4885
US-20200399428-A1 SYSTEMS, METHODS AND HYDROGELS FOR CELL CULTURE AND ANALYSIS HLCS, CD63, CD44 P2RX4 3081/4885BCHE 2942/4885MGLL 1012/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.