Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | WRN | Q14191 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | LPO | P22079 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320438 | 1.00 | P2RX4 (0.48) | P2RX4BCHEMGLLALDH1A1GSK3A | |
| Propionic Acid SCHEMBL28919819 | 0.88 | ALDH1A1 (0.43) | P2RX4BCHEMGLLALDH1A1GSK3A | |
| SCHEMBL13674056 | 0.85 | P2RX4 (0.42) | P2RX4BCHEMGLLALDH1A1GSK3A | |
| SCHEMBL2105111 | 0.78 | P2RX4 (0.40) | P2RX4BCHELPOPSEN1PSEN2 | |
| SCHEMBL1678307 | 0.76 | GSK3A (0.57) | BCHEMGLLALDH1A1GSK3AGSK3B | |
| SCHEMBL19479170 | 0.75 | ALDH1A1 (0.33) | MGLLALDH1A1GSK3AGSK3BBLM | |
| SCHEMBL8014569 | 0.75 | BCHE (0.47) | BCHEMGLLALDH1A1BLMHPGD | |
| SCHEMBL4463617 | 0.73 | ALDH1A1 (0.39) | P2RX4MGLLALDH1A1GSK3AGSK3B | |
| SCHEMBL9642610 | 0.72 | P2RX4 (0.34) | P2RX4BCHEMGLLALDH1A1GSK3A | |
| SCHEMBL18485436 | 0.72 | ALDH1A1 (0.44) | BCHEMGLLALDH1A1GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210347941-A1 | METHOD FOR PREPARING FUNCTIONALIZED POLYMERS FROM POLYMER ALCOHOLS | NEKTAR THERAPEUTICS (US) | 2021-11-11 | — | — | US | disclosed |
| US-10941248-B2 | Methods for preparing functionalized polymers from polymer alcohols | NEKTAR THERAPEUTICS (US) | 2021-03-09 | — | — | US | disclosed |
| US-20190055354-A1 | METHODS FOR PREPARING FUNCTIONALIZED POLYMERS FROM POLYMER ALCOHOLS | NEKTAR THERAPEUTICS | 2019-02-21 | — | — | US | disclosed |
| US-10144804-B2 | Method for preparing functionalized polymers from polymer alcohols | NEKTAR THERAPEUTICS (US) | 2018-12-04 | — | — | US | disclosed |
| US-20170073468-A1 | METHOD FOR PREPARING FUNCTIONALIZED POLYMERS FROM POLYMER ALCOHOLS | NEKTAR THERAPEUTICS | 2017-03-16 | — | — | US | disclosed |
| US-20140073802-A1 | MALEIMIDYL POLYMER DERIVATIVES | NEKTAR THERAPEUTICS (US) | 2014-03-13 | — | — | US | disclosed |
| US-8604159-B2 | Method for preparing functionalized polymers from polymer alcohols | NEKTAR THERAPEUTICS (US) | 2013-12-10 | — | — | US | disclosed |
| EP-1656410-B1 | METHOD FOR PREPARING FUNCTIONALIZED POLYMERS FROM POLYMER ALCOHOLS | NEKTAR THERAPEUTICS (US) | 2010-03-10 | — | — | EP | disclosed |
| EP-1656410-A2 | METHOD FOR PREPARING FUNCTIONALIZED POLYMERS FROM POLYMER ALCOHOLS | Nektar Therapeutics Al, Corporation (US) | 2006-05-17 | — | — | EP | disclosed |
| US-20050054816-A1 | Method for preparing functionalized polymers from polymer alcohols | NEKTAR THERAPEUTICS | 2005-03-10 | — | — | US | disclosed |
| WO-2005010075-A2 | METHOD FOR PREPARING FUNCTIONALIZED POLYMERS FROM POLYMER ALCOHOLS | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2005-02-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210347941-A1 | METHOD FOR PREPARING FUNCTIONALIZED POLYMERS FROM POLYMER ALCOHOLS | ADH1C, ADH1A, ADH5 | P2RX4 4813/4885BCHE 1562/4885MGLL 454/4885 |
| US-10144804-B2 | Method for preparing functionalized polymers from polymer alcohols | ADH1C, ADH1A, ADH5 | P2RX4 4598/4885BCHE 799/4885MGLL 190/4885 |
| US-20190055354-A1 | METHODS FOR PREPARING FUNCTIONALIZED POLYMERS FROM POLYMER ALCOHOLS | ADH1C, ADH1A, ADH5 | P2RX4 4641/4885BCHE 778/4885MGLL 184/4885 |
| US-10941248-B2 | Methods for preparing functionalized polymers from polymer alcohols | ADH1C, ADH1A, ADH5 | P2RX4 4641/4885BCHE 778/4885MGLL 184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.