SCHEMBL8014569

SCHEMBL8014569

CC(C)(C)OC(=O)N1C(=O)C=CC1=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.47
USP2 O75604 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
CTSK P43235 1/20 0.37
MAPT P10636 2/20 0.36
BUB1 O43683 1/20 0.36
KDM4E B2RXH2 1/20 0.36
THRB P10828 1/20 0.36
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
DGAT1 O75907 1/20 0.35
AKT1 P31749 1/20 0.35
CHRM2 P08172 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRM3 P20309 1/20 0.35
FAAH O00519 1/20 0.35
DTYMK P23919 1/20 0.35
ALDH1A1 P00352 2/20 0.34
BLM P54132 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Alanine SCHEMBL28858713 0.86 BCHE (0.39) BCHEMAPTBUB1NFKB1NFKB2
SCHEMBL26985563 0.75 BCHE (0.38) BCHEUSP2SMN1; SMN2MAPTBUB1
SCHEMBL320438 0.75 P2RX4 (0.48) BCHEMAPTALDH1A1BLMGMNN
SCHEMBL3630207 0.75 P2RX4 (0.48) BCHEMAPTALDH1A1BLMGMNN
SCHEMBL9162472 0.74 BCHE (0.43) BCHEUSP2SMN1; SMN2CTSKMAPT
SCHEMBL3748240 0.74 BCHE (0.43) BCHEUSP2SMN1; SMN2CTSKMAPT
SCHEMBL18919395 0.74 BCHE (0.41) BCHEUSP2SMN1; SMN2MAPTBUB1
SCHEMBL10447847 0.72 BCHE (0.42) BCHEUSP2SMN1; SMN2MAPTKDM4E
SCHEMBL5121655 0.72 BCHE (0.54) BCHEBUB1DTYMKALDH1A1GPR119
SCHEMBL1678307 0.71 GSK3A (0.57) BCHESMN1; SMN2MAPTALDH1A1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0492254-B1 Process for the preparation of N-(tert-butoxycarbonyl)maleimide SIEMENS AG (DE) 1999-03-17 EP claimed
US-5691110-A DISSOLVING POLYMER IN SOLVENT; HEATING LUCENT TECHNOLOGIES INC. (US) 1997-11-25 US claimed
EP-0608983-B1 A process for controlled deprotection of polymers and a process for fabricating a device utilizing partially deprotected resist polymers AT & T CORP (US) 1997-11-12 EP claimed
US-5385809-A Partially deprotecting a polymer having a pendant and labile alkoxycarbonyl or alkyl groups prior to use as a photoresist; lithography AT&T CORP. (US) 1995-01-31 US claimed
EP-0608983-A1 A process for controlled deprotection of polymers and a process for fabricating a device utilizing partially deprotected resist polymers AT&T Corp. (US) 1994-08-03 EP claimed
US-5247096-A Reaction of maleimide and di-tert-butyl carbonate in the presence of base HOECHST AKTIENGESELLSCHAFT (DE) 1993-09-21 US claimed
EP-0523556-A1 Process for the production of N-tert.-butoxycarbonyl-maleimide HOECHST AKTIENGESELLSCHAFT (DE) 1993-01-20 EP claimed
EP-0492254-A1 N-(tert-Butoxycarbonyl)maleimide SIEMENS AKTIENGESELLSCHAFT (DE) 1992-07-01 EP claimed
US-5019488-A Method of producing an image reversal negative photoresist having a photo-labile blocked imide HOECHST CELANESE CORPORATION (US) 1991-05-28 US claimed
US-4775609-A Image reversal HOESCHT CELANESE CORPORATION (US) 1988-10-04 US claimed
JP-5262729-A None JP disclosed
EP-4103557-B1 MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2026-02-18 EP disclosed
US-12502378-B2 Monoacylglycerol lipase modulators for use in autism spectrum disorders JANSSEN PHARMACEUTICA NV (BE) 2025-12-23 US disclosed
EP-4384165-B1 MONOACYLGLYCEROL LIPASE MODULATORS FOR USE IN AUTISM SPECTRUM DISORDERS JANSSEN PHARMACEUTICA NV (BE) 2025-07-09 EP disclosed
CN-115066422-B Monoacylglycerol lipase modulators 詹森药业有限公司 2024-11-22 CN disclosed
US-4912018-A High resolution photoresist based on imide containing polymers HOECHST CELANESE CORPORATION (US) 1990-03-27 US disclosed
US-4837124-A High resolution photoresist of imide containing polymers HOECHST CELANESE CORPORATION (US) 1989-06-06 US disclosed
EP-0292821-A2 Image reversal process for normally positive photoresists HOECHST AKTIENGESELLSCHAFT (DE) 1988-11-30 EP disclosed
US-4775609-A Image reversal HOESCHT CELANESE CORPORATION (US) 1988-10-04 US disclosed
EP-0234327-A2 High resolution photoresist of imide containing polymers HOECHST CELANESE CORPORATION (US) 1987-09-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12502378-B2 Monoacylglycerol lipase modulators for use in autism spectrum disorders LIPC, LPL, MGLL BCHE 490/4885USP2 314/4885SMN1; SMN2 2081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.