SCHEMBL3204989

SCHEMBL3204989

Cc1cc(Cl)cc(C(=O)NCC2(C)CC2)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.75

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.40
MALT1 Q9UDY8 2/20 0.35
SLC6A9 P48067 5/20 0.33
NTRK1 P04629 5/20 0.33
P2RX7 Q99572 2/20 0.33
DRD4 P21917 1/20 0.32
KIF18A Q8NI77 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15698529 0.93 DHODH (0.37) DHODHMALT1SLC6A9NTRK1
SCHEMBL2083746 0.89 DHODH (0.42) DHODHMALT1NTRK1
SCHEMBL2293991 0.88 P2RX7 (0.35) MALT1SLC6A9NTRK1P2RX7
SCHEMBL4168969 0.88 DHODH (0.41) DHODHMALT1NTRK1KIF18A
SCHEMBL31621733 0.87 DHODH (0.42) DHODHMALT1NTRK1
SCHEMBL950846 0.87 DHODH (0.44) DHODHMALT1NTRK1P2RX7DRD4
SCHEMBL2138302 0.86 P2RX7 (0.41) DHODHMALT1P2RX7DRD4
SCHEMBL28425563 0.86 DHODH (0.41) DHODHMALT1NTRK1P2RX7DRD4
Chlorantraniliprole SCHEMBL29551 0.86 DHODH (0.44) DHODHMALT1NTRK1DRD4
Chlorantraniliprole SCHEMBL29363261 0.86 DHODH (0.44) DHODHMALT1NTRK1DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100035935-A1 ANTHRANILAMIDE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND PESTICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA, LTD. (JP) 2010-02-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100035935-A1 ANTHRANILAMIDE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND PESTICIDES CONTAINING THEM AADAC, ANTXR2, DDT DHODH 141/4885MALT1 4311/4885SLC6A9 3710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.