Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cephapirin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 8/20 | 0.84 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.84 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.84 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.84 |
| ▸ | POLB | P06746 | 3/20 | 0.84 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.84 |
| ▸ | APEX1 | P27695 | 2/20 | 0.84 |
| ▸ | LMNA | P02545 | 2/20 | 0.84 |
| ▸ | RECQL | P46063 | 1/20 | 0.84 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.84 |
| ▸ | CA5A | P35218 | 1/20 | 0.77 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.66 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.66 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.66 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.66 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.66 |
| ▸ | ESR1 | P03372 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cephapirin SCHEMBL11844804 | 1.00 | NR1I2 (1.00) | NR1I2MAPTTDP1CYP3A4L3MBTL1 | |
| Cephapirin SCHEMBL11844793 | 1.00 | NR1I2 (1.00) | NR1I2MAPTTDP1CYP3A4L3MBTL1 | |
| Cephapirin SCHEMBL16072823 | 1.00 | NR1I2 (1.00) | NR1I2MAPTTDP1CYP3A4L3MBTL1 | |
| Cephapirin SCHEMBL8194062 | 1.00 | NR1I2 (1.00) | NR1I2MAPTTDP1CYP3A4L3MBTL1 | |
| Cephapirin SCHEMBL28932665 | 0.99 | NR1I2 (0.98) | NR1I2MAPTTDP1CYP3A4L3MBTL1 | |
| Cephapirin SCHEMBL9437555 | 0.99 | NR1I2 (0.98) | NR1I2MAPTTDP1CYP3A4L3MBTL1 | |
| Cephapirin SCHEMBL151779 | 0.99 | NR1I2 (0.98) | NR1I2MAPTTDP1CYP3A4L3MBTL1 | |
| Cephapirin SCHEMBL10275188 | 0.94 | NR1I2 (0.88) | NR1I2MAPTTDP1CYP3A4L3MBTL1 | |
| Cephapirin SCHEMBL4190569 | 0.92 | NR1I2 (0.84) | NR1I2MAPTTDP1CYP3A4L3MBTL1 | |
| Cephapirin SCHEMBL467178 | 0.92 | NR1I2 (0.84) | NR1I2MAPTTDP1CYP3A4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 11858 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637481-B2 | Boronic acid derivatives and therapeutic uses thereof | QPEX BIOPHARMA, INC. (US) | 2026-05-26 | — | — | US | claimed |
| US-12629336-B2 | Compositions and methods of use thereof for treatment of mastitis | CUREMAST, INC. (US) | 2026-05-19 | — | — | US | claimed |
| US-20260108619-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2026-04-23 | — | — | US | claimed |
| US-12576124-B2 | Formulation of a conjugate of a tubulysin analog to a cell-binding molecule | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2026-03-17 | — | — | US | claimed |
| EP-4680248-A1 | PRODUCTS OF MANUFACTURE AND THERAPEUTIC COMPOSITIONS FOR TREATING, AMELIORATING OR PREVENTING VIRAL INFECTIONS AND METHODS FOR MAKING AND USING THEM | Topelia Aust Limited (ACN 652 771 670) (AU) | 2026-01-21 | — | — | EP | claimed |
| US-20260002180-A1 | PLATFORM FOR BIO-BASED PRODUCTION OF HIGH LEVELS OF O-PHOSPHOSERINE, CYSTEATE, OR TAURINE | NATÁUR INC. (US) | 2026-01-01 | — | — | US | claimed |
| EP-4659014-A1 | EMULSION-BASED THICK-FILM ANTIFOULING COATING FOR HIGHLY SENSITIVE ELECTROCHEMICAL SENSING | President And Fellows Of Harvard College (US) | 2025-12-10 | — | — | EP | claimed |
| US-20250339551-A1 | AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE DIFFERENT FUNCTIONAL SMALL MOLECULES FOR ENHANCED TREATMENT OF REFRACTORY DISEASES | HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) | 2025-11-06 | — | — | US | claimed |
| EP-4642492-A1 | AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE FUNCTIONAL SMALL MOLECULE COMPOUNDS FOR ENHANCED TREATMENT OF REFRACTORY DISEASES | Hangzhou Seehe Biotechnology Co., Ltd (CN) | 2025-11-05 | — | — | EP | claimed |
| EP-4642484-A1 | TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE | Hangzhou Seehe Biotechnology Co., Ltd (CN) | 2025-11-05 | — | — | EP | claimed |
| EP-0056560-A1 | Active antibiotic compositions, process for their manufacture and process for the antibiotic activity of antibiotics | CIBA-GEIGY AG (CH) | 1982-07-28 | — | — | EP | claimed |
| EP-0055870-A1 | Pyridylmethyl esters of selected bio-affecting carboxylic acids, process for preparing and pharmaceutical composition comprising the same | MERCK & CO. INC. (US) | 1982-07-14 | — | — | EP | claimed |
| EP-0051278-A1 | Soft tertiary amine esters of bio-affecting carboxylic acids, processes for preparing and a pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1982-05-12 | — | — | EP | claimed |
| EP-0050805-A1 | Beta-lactams, intermediates and process for their preparation, and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-05-05 | — | — | EP | claimed |
| EP-0036534-A1 | An orally administrable drug form comprising a beta-lactam antibiotic and an adjuvant | INTERx RESEARCH CORPORATION (US) | 1981-09-30 | — | — | EP | claimed |
| US-4287181-A | TO ENHANCE THE EFFECTIVENESS OF B-LACTAM ANTIBIOTICS | PFIZER INC. (US) | 1981-09-01 | — | — | US | claimed |
| US-4260598-A | ADMINISTERING 6-AMINOPENICILLANIC ACID 1,1-DIOXIDE OR ESTERS THEREOF | PFIZER INC. (US) | 1981-04-07 | — | — | US | claimed |
| US-4256733-A | Acetoxymethyl penam compounds as β-lactamase inhibitors | PFIZER INC. (US) | 1981-03-17 | — | — | US | claimed |
| EP-0008917-A1 | Penam-3-carboxylic acid 1,1-dioxides, process for their preparation and pharmaceutical compositions | PFIZER INC. (US) | 1980-03-19 | — | — | EP | claimed |
| EP-0007717-A1 | Clavulanic acid derivatives, a process for their preparation, their use, and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1980-02-06 | — | — | EP | claimed |