Cephapirin

Cephapirin

SCHEMBL467178

CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)CSc3ccncc3)[C@H]2SC1.CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)CSc3ccncc3)[C@H]2SC1.c1ccc(CNCCNCc2ccccc2)cc1

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Cephapirin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1I2 O75469 3/20 0.84
MAPT P10636 8/20 0.72
TDP1 Q9NUW8 7/20 0.72
CYP3A4 P08684 4/20 0.72
L3MBTL1 Q9Y468 4/20 0.72
HSD17B10 Q99714 3/20 0.72
POLB P06746 3/20 0.72
KDM4E B2RXH2 2/20 0.72
APEX1 P27695 2/20 0.72
LMNA P02545 2/20 0.72
RECQL P46063 1/20 0.72
CYP2D6 P10635 1/20 0.72
CA5A P35218 1/20 0.66
CTDSP1 Q9GZU7 2/20 0.59
HPGD P15428 2/20 0.59
DNMT1 P26358 1/20 0.59
SLC22A6 Q4U2R8 1/20 0.59
SLC22A8 Q8TCC7 1/20 0.59
SLC22A11 Q9NSA0 1/20 0.59
PTGS1 P23219 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cephapirin SCHEMBL4190569 1.00 NR1I2 (0.84) NR1I2MAPTTDP1CYP3A4L3MBTL1
Cephapirin SCHEMBL16072823 0.92 NR1I2 (1.00) NR1I2MAPTTDP1CYP3A4L3MBTL1
Cephapirin SCHEMBL11844793 0.92 NR1I2 (1.00) NR1I2MAPTTDP1CYP3A4L3MBTL1
Cephapirin SCHEMBL11844804 0.92 NR1I2 (1.00) NR1I2MAPTTDP1CYP3A4L3MBTL1
Cephapirin SCHEMBL8194062 0.92 NR1I2 (1.00) NR1I2MAPTTDP1CYP3A4L3MBTL1
Cephapirin SCHEMBL3205 0.92 NR1I2 (1.00) NR1I2MAPTTDP1CYP3A4L3MBTL1
Cephapirin SCHEMBL9437555 0.91 NR1I2 (0.98) NR1I2MAPTTDP1CYP3A4L3MBTL1
Cephapirin SCHEMBL151779 0.91 NR1I2 (0.98) NR1I2MAPTTDP1CYP3A4L3MBTL1
Cephapirin SCHEMBL28932665 0.91 NR1I2 (0.98) NR1I2MAPTTDP1CYP3A4L3MBTL1
Cephapirin SCHEMBL10275188 0.86 NR1I2 (0.88) NR1I2MAPTTDP1CYP3A4L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11124758-B2 Bacteria culture medium and applications thereof SHANGHAI PROMOTON BIOTECHNOLOGY CO., LTD. (CN) 2021-09-21 US claimed
EP-3018134-B1 BACTERIA CULTURE MEDIUM AND USE THEREOF SHANGHAI PROMOTON BIOTECHNOLOGY CO LTD (CN) 2018-04-04 EP claimed
US-20170112829-A1 USE OF COMPOUNDS BINDING TO THE SIGMA RECEPTOR LIGANDS FOR THE TREATMENT OF NEUROPATHIC PAIN DEVELOPING AS A CONSEQUENCE OF CHEMOTHERAPY LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2017-04-27 US claimed
EP-3018134-A1 BACTERIA CULTURE MEDIUM AND USE THEREOF Shanghai Promoton Biotechnology Co., Ltd (CN) 2016-05-11 EP claimed
US-20160097030-A1 Bacteria Culture Medium and Applications Thereof NANTONG BROTH BIOTECHNOLOGY CO., LTD (CN) 2016-04-07 US claimed
CN-103396968-B Bacteria culture medium and application thereof SHANGHAI QIDONGYUAN BIOLOG SCIENT CO LTD 2015-03-25 CN claimed
CN-103230366-B Novel slow-release breast perfusion agent for preventing cow subclinical mastitis and preparation method thereof CHINA ANIMAL HUSBANDRY COMMERICAL (GROUP) GEN. CORP. (CN) 2014-10-01 CN claimed
CN-103396968-A Bacteria culture medium and application thereof SHANGHAI PROMOTON BIOLOG SCIENT CO LTD 2013-11-20 CN claimed
CN-103230366-A Novel slow-release breast perfusion agent for preventing cow subclinical mastitis and preparation method thereof CHINA ANIMAL HUSBANDRY GROUP 2013-08-07 CN claimed
CN-102020665-B Method for preparing cephapirin benzathine GUANGZHOU BAIYUNSHAN PHARMACEUTICAL FACTORY GUANGZHOU BAIYUNSHAN PHARMACEUTICAL CO LTD 2012-09-19 CN claimed
CN-101781317-B Method for preparing cephapirin benzathine GUANGZHOU BAIYUNSHAN PHARMACEUTICAL FACTORY GUANGZHOU BAIYUNSHAN PHARMACEUTICAL CO LTD 2012-03-28 CN claimed
CN-102020665-A Method for preparing cephapirin benzathine GUANGZHOU BAIYUNSHAN PHARMACEUTICAL FACTORY GUANGZHOU BAIYUNSHAN PHARMACEUTICAL CO LTD 2011-04-20 CN claimed
US-20110052723-A1 USE OF COMPOUNDS BINDING TO THE SIGMA RECEPTOR LIGANDS FOR THE TREATMENT OF NEUROPATHIC PAIN DEVELOPING AS A CONSEQUENCE OF CHEMOTHERAPY LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2011-03-03 US claimed
CN-101781317-A Method for preparing cephapirin benzathine GUANGZHOU BAIYUNSHAN PHARMACEU 2010-07-21 CN claimed
US-20090325975-A1 Use of compounds binding to the sigma receptor for the treatment of diabetes-associated pain LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2009-12-31 US claimed
EP-2090311-A1 Use of compounds binding to the sigma receptor ligands for the treatment of neuropathic pain developing as a consequence of chemotherapy Laboratorios Del. Dr. Esteve, S.A. (ES) 2009-08-19 EP claimed
US-20090042898-A1 USE OF COMPOUNDS ACTIVE ON THE SIGMA RECEPTOR FOR THE TREATMENT OF MECANICAL ALLODYNIA LABORATORIOS DEL DR. ESTEVE S.A. (ES) 2009-02-12 US claimed
EP-1829534-A1 Use of compounds binding to the sigma receptor for the treatment of metabolic syndrome LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2007-09-05 EP claimed
EP-1787679-A1 Use of compounds binding to the sigma receptor for the treatment of diabetes-associated pain LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2007-05-23 EP claimed
EP-2819699-B2 CONTROLLED RELEASE COMPOSITIONS AND THEIR METHODS OF USE Elanco New Zealand (NZ) 2024-10-16 EP disclosed
CN-115664779-A Method, device and equipment for detecting abnormal flow of industrial network and storage medium 杭州安恒信息技术股份有限公司 2023-01-31 CN disclosed
US-20230001128-A1 AEROSOLIZATION SYSTEMS, METHODS, AND APPARATUSES SHUSTER GARY STEPHEN (CA) 2023-01-05 US disclosed
US-11311582-B2 Bacteriophage compositions and methods of use thereof Locus Biosciences, Inc. (US) 2022-04-26 US disclosed
US-11124758-B2 Bacteria culture medium and applications thereof SHANGHAI PROMOTON BIOTECHNOLOGY CO., LTD. (CN) 2021-09-21 US disclosed
US-10828311-B2 Controlled release compositions and their methods of use BAYER NEW ZEALAND LIMITED (NZ) 2020-11-10 US disclosed
EP-3694489-A2 METHODS AND COMPOSITIONS FOR TOPICAL DELIVERY Illustris Pharmaceuticals, Inc. (US) 2020-08-19 EP disclosed
CN-110228897-A Drainage processing method and disintegrating system in waste pipe 日立造船株式会社 2019-09-13 CN disclosed
EP-2819699-B1 CONTROLLED RELEASE COMPOSITIONS AND THEIR METHODS OF USE BAYER NEW ZEALAND LTD (NZ) 2019-05-22 EP disclosed
WO-2019075263-A2 METHODS AND COMPOSITIONS FOR TOPICAL DELIVERY ILLUSTRIS PHARMACEUTICALS, INC. (US) 2019-04-18 WO disclosed
US-20190105261-A1 METHODS AND COMPOSITIONS FOR TOPICAL DELIVERY ILLUSTRIS PHARMACEUTICALS, INC. 2019-04-11 US disclosed
EP-3442488-A1 COMPOSITIONS FOR TOPICAL APPLICATION OF COMPOUNDS Illustris Pharmaceuticals, Inc. (US) 2019-02-20 EP disclosed
US-20190015475-A1 CASEIN PEPTIDE FOR USE IN THE TREATMENT OF UTERINE INFECTIONS MILEUTIS LTD. (IL) 2019-01-17 US disclosed
US-20190008795-A1 COMPOSITIONS FOR TOPICAL APPLICATION OF COMPOUNDS ILLUSTRIS PHARMACEUTICALS, INC. 2019-01-10 US disclosed
EP-3018134-B1 BACTERIA CULTURE MEDIUM AND USE THEREOF SHANGHAI PROMOTON BIOTECHNOLOGY CO LTD (CN) 2018-04-04 EP disclosed
EP-2600863-B1 USE OF SIGMA LIGANDS IN OPIOID-INDUCED HYPERALGESIA ESTEVE LABOR DR (ES) 2018-03-28 EP disclosed
US-9861678-B2 Casein peptide for use in the treatment of uterine infections MILEUTIS LTD. (IL) 2018-01-09 US disclosed
US-9844516-B2 Sigma ligands for use in the prevention and/or treatment of post-operative pain Laboratorios De Dr. Esteve (ES) 2017-12-19 US disclosed
WO-2017180788-A1 COMPOSITIONS FOR TOPICAL APPLICATION OF COMPOUNDS ILLUSTRIS PHARMACEUTICALS, INC. (US) 2017-10-19 WO disclosed
US-9789115-B2 Use of sigma ligands in opioid-induced hyperalgesia LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2017-10-17 US disclosed
US-20170290778-A1 COMPOSITIONS FOR TOPICAL APPLICATION OF COMPOUNDS ILLUSTRIS PHARMACEUTICALS, INC. 2017-10-12 US disclosed
US-9782483-B2 Sigma ligands for the prevention and/or treatment of emesis induced by chemotherapy or radiotherapy LABORATORIES DEL DR. ESTEVE, S.A. (ES) 2017-10-10 US disclosed
EP-2560669-B2 CASEIN PEPTIDE FOR USE IN THE TREATMENT OF UTERINE INFECTIONS MILEUTIS LTD (IL) 2017-10-04 EP disclosed
US-20170112829-A1 USE OF COMPOUNDS BINDING TO THE SIGMA RECEPTOR LIGANDS FOR THE TREATMENT OF NEUROPATHIC PAIN DEVELOPING AS A CONSEQUENCE OF CHEMOTHERAPY LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2017-04-27 US disclosed
EP-2646025-B1 USE OF SIGMA LIGANDS IN BONE CANCER PAIN ESTEVE LABOR DR (ES) 2017-03-15 EP disclosed
US-20160367580-A1 IMPROVED EXTENDED-ACTION TILMICOSIN AND USE THEREOF IN TREATMENT OF BOVINE RESPIRATORY DISEASE COMPLEX (BRD) AND IN DRY COW PERIOD UNIVERSIDAD NACIONAL AUTONOMA DE MEXICO (MX) 2016-12-22 US disclosed
US-20160324915-A1 Casein Peptide for Use in the Treatment of Uterine Infections MILEUTIS LTD. (IL) 2016-11-10 US disclosed
EP-3018134-A1 BACTERIA CULTURE MEDIUM AND USE THEREOF Shanghai Promoton Biotechnology Co., Ltd (CN) 2016-05-11 EP disclosed
US-20160097030-A1 Bacteria Culture Medium and Applications Thereof NANTONG BROTH BIOTECHNOLOGY CO., LTD (CN) 2016-04-07 US disclosed
EP-2531191-B1 Sigma ligands for use in the prevention and/or treatment of postoperative pain ESTEVE LABOR DR (ES) 2016-03-30 EP disclosed
CN-102933223-B Casein peptides for the treatment of uterine infections MILEUTIS LTD. (IL) 2016-03-09 CN disclosed
EP-2571501-B1 SIGMA LIGANDS FOR THE PREVENTION AND/OR TREATMENT OF EMESIS INDUCED BY CHEMOTHERAPY OR RADIOTHERAPY ESTEVE LABOR DR (ES) 2016-03-02 EP disclosed
US-9220751-B2 Casein peptide for use in the treatment of uterine infections MILEUTIS LTD. (IL) 2015-12-29 US disclosed
CN-103396968-B Bacteria culture medium and application thereof SHANGHAI QIDONGYUAN BIOLOG SCIENT CO LTD 2015-03-25 CN disclosed
WO-2015021692-A1 BACTERIA CULTURE MEDIUM AND USE THEREOF 上海启动元生物科技有限公司 (CN) 2015-02-19 WO disclosed
US-20150045337-A1 CONTROLLED RELEASE COMPOSITIONS AND THEIR METHODS OF USE Elanco New Zealand (NZ) 2015-02-12 US disclosed
EP-2819699-A1 CONTROLLED RELEASE COMPOSITIONS AND THEIR METHODS OF USE Bayer New Zealand Limited (NZ) 2015-01-07 EP disclosed
CN-104244983-A Controlled release compositions and methods of use thereof BAYER NEW ZEALAND LTD 2014-12-24 CN disclosed
CN-103230366-B Novel slow-release breast perfusion agent for preventing cow subclinical mastitis and preparation method thereof CHINA ANIMAL HUSBANDRY COMMERICAL (GROUP) GEN. CORP. (CN) 2014-10-01 CN disclosed
CN-103230366-B Novel slow-release breast perfusion agent for preventing cow subclinical mastitis and preparation method thereof CHINA ANIMAL HUSBANDRY COMMERICAL (GROUP) GEN. CORP. (CN) 2014-10-01 CN disclosed
US-20130324535-A1 USE OF SIGMA LIGANDS IN BONE CANCER PAIN LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2013-12-05 US disclosed
CN-103396968-A Bacteria culture medium and application thereof SHANGHAI PROMOTON BIOLOG SCIENT CO LTD 2013-11-20 CN disclosed
WO-2013129944-A1 CONTROLLED RELEASE COMPOSITIONS AND THEIR METHODS OF USE BAYER NEW ZEALAND LIMITED (NZ) 2013-09-06 WO disclosed
CN-103230366-A Novel slow-release breast perfusion agent for preventing cow subclinical mastitis and preparation method thereof CHINA ANIMAL HUSBANDRY GROUP 2013-08-07 CN disclosed
CN-103230366-A Novel slow-release breast perfusion agent for preventing cow subclinical mastitis and preparation method thereof CHINA ANIMAL HUSBANDRY GROUP 2013-08-07 CN disclosed
US-20130158033-A1 USE OF SIGMA LIGANDS IN OPIOID-INDUCED HYPERALGESIA LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2013-06-20 US disclosed
US-20130109634-A1 Casein Peptide For Use In The Treatment Of Uterine Infections MILEUTIS, LTD. (IL) 2013-05-02 US disclosed
US-20130109692-A1 SIGMA LIGANDS FOR THE PREVENTION AND/OR TREATMENT OF EMESIS INDUCED BY CHEMOTHERAPY OR RADIOTHERAPY LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2013-05-02 US disclosed
EP-2560669-A1 CASEIN PEPTIDE FOR USE IN THE TREATMENT OF UTERINE INFECTIONS Mileutis Ltd. (IL) 2013-02-27 EP disclosed
CN-102933223-A Casein peptides for the treatment of uterine infections MILEUTIS LTD 2013-02-13 CN disclosed
CN-101107015-B Injection for mastitis NIPPON ZENYAKU KOGYO KK 2013-01-23 CN disclosed
US-20120302568-A1 SIGMA LIGANDS FOR USE IN THE PREVENTION AND/OR TREATMENT OF POST-OPERATIVE PAIN LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2012-11-29 US disclosed
CN-102020665-B Method for preparing cephapirin benzathine GUANGZHOU BAIYUNSHAN PHARMACEUTICAL FACTORY GUANGZHOU BAIYUNSHAN PHARMACEUTICAL CO LTD 2012-09-19 CN disclosed
CN-102020665-B Method for preparing cephapirin benzathine GUANGZHOU BAIYUNSHAN PHARMACEUTICAL FACTORY GUANGZHOU BAIYUNSHAN PHARMACEUTICAL CO LTD 2012-09-19 CN disclosed
CN-102020665-B Method for preparing cephapirin benzathine GUANGZHOU BAIYUNSHAN PHARMACEUTICAL FACTORY GUANGZHOU BAIYUNSHAN PHARMACEUTICAL CO LTD 2012-09-19 CN disclosed
EP-2460519-A1 Use of sigma ligands in bone cancer pain Laboratorios Del. Dr. Esteve, S.A. (ES) 2012-06-06 EP disclosed
CN-101781317-B Method for preparing cephapirin benzathine GUANGZHOU BAIYUNSHAN PHARMACEUTICAL FACTORY GUANGZHOU BAIYUNSHAN PHARMACEUTICAL CO LTD 2012-03-28 CN disclosed
CN-101781317-B Method for preparing cephapirin benzathine GUANGZHOU BAIYUNSHAN PHARMACEUTICAL FACTORY GUANGZHOU BAIYUNSHAN PHARMACEUTICAL CO LTD 2012-03-28 CN disclosed
CN-101781317-B Method for preparing cephapirin benzathine GUANGZHOU BAIYUNSHAN PHARMACEUTICAL FACTORY GUANGZHOU BAIYUNSHAN PHARMACEUTICAL CO LTD 2012-03-28 CN disclosed
EP-2415471-A1 Use of sigma ligands in opioid-induced hyperalgesia Laboratorios Del. Dr. Esteve, S.A. (ES) 2012-02-08 EP disclosed
EP-2388005-A1 Sigma ligands for the prevention and/or treatment of emesis induced by chemotherapy or radiotherapy Laboratorios Del. Dr. Esteve, S.A. (ES) 2011-11-23 EP disclosed
WO-2011132191-A1 CASEIN PEPTIDE FOR USE IN THE TREATMENT OF UTERINE INFECTIONS MILEUTIS LTD. (IL) 2011-10-27 WO disclosed
EP-2353598-A1 Sigma ligands for use in the prevention and/or treatment of postoperative pain Laboratorios Del. Dr. Esteve, S.A. (ES) 2011-08-10 EP disclosed
CN-102020665-A Method for preparing cephapirin benzathine GUANGZHOU BAIYUNSHAN PHARMACEUTICAL FACTORY GUANGZHOU BAIYUNSHAN PHARMACEUTICAL CO LTD 2011-04-20 CN disclosed
CN-102020665-A Method for preparing cephapirin benzathine GUANGZHOU BAIYUNSHAN PHARMACEUTICAL FACTORY GUANGZHOU BAIYUNSHAN PHARMACEUTICAL CO LTD 2011-04-20 CN disclosed
CN-102020665-A Method for preparing cephapirin benzathine GUANGZHOU BAIYUNSHAN PHARMACEUTICAL FACTORY GUANGZHOU BAIYUNSHAN PHARMACEUTICAL CO LTD 2011-04-20 CN disclosed
US-20110052723-A1 USE OF COMPOUNDS BINDING TO THE SIGMA RECEPTOR LIGANDS FOR THE TREATMENT OF NEUROPATHIC PAIN DEVELOPING AS A CONSEQUENCE OF CHEMOTHERAPY LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2011-03-03 US disclosed
CN-101781317-A Method for preparing cephapirin benzathine GUANGZHOU BAIYUNSHAN PHARMACEU 2010-07-21 CN disclosed
CN-101781317-A Method for preparing cephapirin benzathine GUANGZHOU BAIYUNSHAN PHARMACEU 2010-07-21 CN disclosed
CN-101781317-A Method for preparing cephapirin benzathine GUANGZHOU BAIYUNSHAN PHARMACEU 2010-07-21 CN disclosed
US-20090325975-A1 Use of compounds binding to the sigma receptor for the treatment of diabetes-associated pain LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2009-12-31 US disclosed
US-20090312380-A1 NOVEL COMPOSITIONS AND METHODS GENERICS [UK] LIMITED (GB) 2009-12-17 US disclosed
WO-2009120182-A2 SULFO-POLYMER POWDER AND SULFO-POLYMER POWDER BLENDS WITH CARRIERS AND/OR ACTIVES EASTMAN CHEMICAL COMPANY (US) 2009-10-01 WO disclosed
EP-2090311-A1 Use of compounds binding to the sigma receptor ligands for the treatment of neuropathic pain developing as a consequence of chemotherapy Laboratorios Del. Dr. Esteve, S.A. (ES) 2009-08-19 EP disclosed
US-20090181976-A1 Use of Compounds Binding to the Sigma Receptor for the Treatment of Metabolic Syndrome LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2009-07-16 US disclosed
US-20090163449-A1 SULFO-POLYMER POWDER AND SULFO-POLYMER POWDER BLENDS WITH CARRIERS AND/OR ADDITIVES EASTMAN CHEMICAL COMPANY (US) 2009-06-25 US disclosed
EP-2056875-A1 NOVEL COMPOSITIONS AND METHODS Generics (UK) Limited (GB) 2009-05-13 EP disclosed
US-20090042898-A1 USE OF COMPOUNDS ACTIVE ON THE SIGMA RECEPTOR FOR THE TREATMENT OF MECANICAL ALLODYNIA LABORATORIOS DEL DR. ESTEVE S.A. (ES) 2009-02-12 US disclosed
WO-2008026012-A1 NOVEL COMPOSITIONS AND METHODS GENERICS [UK] LIMITED (GB) 2008-03-06 WO disclosed
CN-101107015-A Injection for mastitis NIPPON ZENYAKU KOGYO KK (JP) 2008-01-16 CN disclosed
EP-1829534-A1 Use of compounds binding to the sigma receptor for the treatment of metabolic syndrome LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2007-09-05 EP disclosed
CN-1988896-A Use of compounds active on the sigma receptor for the treatment of mechanical allodynia ESTEVE LABOR DR (ES) 2007-06-27 CN disclosed
EP-1787679-A1 Use of compounds binding to the sigma receptor for the treatment of diabetes-associated pain LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2007-05-23 EP disclosed
EP-1787679-A1 Use of compounds binding to the sigma receptor for the treatment of diabetes-associated pain LABORATORIOS DEL DR. ESTEVE, S.A. (ES) 2007-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160367580-A1 IMPROVED EXTENDED-ACTION TILMICOSIN AND USE THEREOF IN TREATMENT OF BOVINE RESPIRATORY DISEASE COMPLEX (BRD) AND IN DRY COW PERIOD BTD, LTA, SBDS NR1I2 2486/4885MAPT 1240/4885TDP1 2322/4885
US-20120302568-A1 SIGMA LIGANDS FOR USE IN THE PREVENTION AND/OR TREATMENT OF POST-OPERATIVE PAIN OPRL1, OPRK1, SIGMAR1 NR1I2 378/4885MAPT 3625/4885TDP1 2716/4885
US-20130158033-A1 USE OF SIGMA LIGANDS IN OPIOID-INDUCED HYPERALGESIA OPRL1, OPRK1, OPRM1 NR1I2 119/4885MAPT 1420/4885TDP1 4291/4885
US-20090042898-A1 USE OF COMPOUNDS ACTIVE ON THE SIGMA RECEPTOR FOR THE TREATMENT OF MECANICAL ALLODYNIA OPRM1, OPRL1, OPRK1 NR1I2 793/4885MAPT 917/4885TDP1 3956/4885
US-20090181976-A1 Use of Compounds Binding to the Sigma Receptor for the Treatment of Metabolic Syndrome SIGMAR1, GPR119, TMEM97 NR1I2 53/4885MAPT 3205/4885TDP1 4408/4885
US-20130109692-A1 SIGMA LIGANDS FOR THE PREVENTION AND/OR TREATMENT OF EMESIS INDUCED BY CHEMOTHERAPY OR RADIOTHERAPY SIGMAR1, SFN, TMEM97 NR1I2 177/4885MAPT 4002/4885TDP1 1095/4885
US-20130324535-A1 USE OF SIGMA LIGANDS IN BONE CANCER PAIN SIGMAR1, OPRL1, OPRK1 NR1I2 37/4885MAPT 4337/4885TDP1 4264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.