Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3214074 | 0.88 | ALDH1A1 (0.34) | ALDH1A1CYP3A4CYP2D6TSHRMAPT | |
| SCHEMBL9701624 | 0.77 | GAA (0.43) | ALDH1A1CYP3A4CYP2D6TSHRMAPT | |
| SCHEMBL6414324 | 0.75 | LMNA (0.38) | ALDH1A1CYP3A4CYP2D6TSHRMAPT | |
| SCHEMBL4963357 | 0.75 | CYP2D6 (0.39) | ALDH1A1CYP3A4CYP2D6TSHRMAPT | |
| SCHEMBL15878904 | 0.75 | CYP2D6 (0.39) | ALDH1A1CYP3A4CYP2D6TSHRMAPT | |
| SCHEMBL450129 | 0.75 | CYP2D6 (0.39) | ALDH1A1CYP3A4CYP2D6TSHRMAPT | |
| SCHEMBL450130 | 0.75 | CYP2D6 (0.39) | ALDH1A1CYP3A4CYP2D6TSHRMAPT | |
| SCHEMBL3214114 | 0.74 | LMNA (0.37) | SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL6414083 | 0.73 | PRMT5 (0.39) | ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL1872709 | 0.70 | CA2 (0.47) | ALDH1A1CYP3A4CYP2D6TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | WYETH | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | HTR2C, HTR5A, NPY1R | ALDH1A1 1164/4885CYP3A4 298/4885CYP2D6 554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.