SCHEMBL320541

SCHEMBL320541

CC(C)(C)OC(=O)N=C(N)N

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.34
CTSK P43235 1/20 0.32
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
NOS1 P29475 2/20 0.30
NOS3 P29474 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17348031 0.83 DGAT1 (0.33) DGAT1MAOAMAOB
SCHEMBL6562049 0.81 DGAT1 (0.32) DGAT1
SCHEMBL8750078 0.79 DGAT1 (0.31) DGAT1
SCHEMBL8879857 0.79 DGAT1 (0.31) DGAT1
SCHEMBL1136775 0.78 NOS1 (0.43) DGAT1NOS1NOS3NOS2
SCHEMBL15324947 0.78 DGAT1 (0.30) DGAT1
SCHEMBL28705194 0.78 DGAT1 (0.34) DGAT1MAOAMAOBNOS1
SCHEMBL12317214 0.78 NOS1 (0.43) DGAT1NOS1NOS3NOS2
SCHEMBL6379683 0.78 DGAT1 (0.34) DGAT1CTSKMAOAMAOBNOS1
SCHEMBL1136772 0.78 NOS1 (0.43) DGAT1NOS1NOS3NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 309 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118994019-A Process for the preparation of (R) -2- ((R) -2' -amino-4 ',5' -dihydro-1 ' H-imidazol-4 ' -yl) -6-methylhept-5-enoate derivatives 临沂大学 2024-11-22 CN claimed
CN-115028554-B Guanfacine hydrochloride and preparation method thereof 海南慧谷药业有限公司 2023-04-28 CN claimed
CN-110698413-B Substituted pyrimidine derivative containing guanidyl, pharmaceutical composition thereof, and preparation method and application thereof 中国海洋大学 2023-01-24 CN claimed
CN-115028554-A Guanfacine hydrochloride and preparation method thereof 广东科泰鼎润药业科技有限公司 2022-09-09 CN claimed
CN-112375055-A Preparation method of eptifibatide key raw material L-high arginine 宁夏蓝博思化学技术有限公司 2021-02-19 CN claimed
CN-112358423-A Preparation and application of novel polypeptide guanidizing agent 宁夏蓝博思化学技术有限公司 2021-02-12 CN claimed
CN-110698413-A Substituted pyrimidine derivative containing guanidyl, pharmaceutical composition thereof, and preparation method and application thereof 中国海洋大学 2020-01-17 CN claimed
CN-108869233-A A kind of small-sized pressure stabilizing long axis Fire Fighting Pumps using novel coolant 贝德科技有限公司 2018-11-23 CN claimed
CN-102753546-A 5-membered heterocyclic derivatives and process for producing the same ILDONG PHARM CO LTD 2012-10-24 CN claimed
CN-102134210-A Leonurine derivative and preparation method thereof UNIV FUDAN 2011-07-27 CN claimed
US-20260138957-A1 UREA-LINKED 2-AMINOIMIDAZOLE DIMER POTENTIATORS UNIVERSITY OF NOTRE DAME DU LAC (US) 2026-05-21 US disclosed
US-20260083865-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS AND USE THEREOF 3B PHARMACEUTICALS GMBH (DE) 2026-03-26 US disclosed
EP-3597184-B1 INDANONE DERIVATIVES, PHARMACEUTICALLY ACCEPTABLE SALTS OR OPTICAL ISOMERS THEREOF, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING VIRAL DISEASES KOREA RES INST CHEMICAL TECH (KR) 2026-03-04 EP disclosed
US-12559461-B2 Antibiotic adjuvant compounds UNIVERSITY OF NOTRE DAME DU LAC (US) 2026-02-24 US disclosed
EP-3727435-B1 BIVALENT NUCLEIC ACID LIGANDS AND USES THEREFOR UNIV CARNEGIE MELLON (US) 2026-02-18 EP disclosed
EP-0754184-A1 CEPHALOSPORIN ANTIBIOTICS Microcide Pharmaceuticals, Inc. (US) 1997-01-22 EP disclosed
WO-1996038450-A1 CEPHALOSPORIN ANTIBIOTICS MICROCIDE PHARMACEUTICALS, INC. (US) 1996-12-05 WO disclosed
WO-1995026966-A1 CEPHALOSPORIN ANTIBIOTICS MICROCIDE PHARMACEUTICALS, INC. (US) 1995-10-12 WO disclosed
CN-1098722-A Tricyclic quinoxalinedione derivatives SUMITOMO PHARMA (JP) 1995-02-15 CN disclosed
CN-1040582-A New peptidase inhibitors MERRELL DOW PHARMA (US) 1990-03-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083865-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS AND USE THEREOF KLK3, FOLH1, PSMA1 DGAT1 4765/4885CTSK 1726/4885MAOA 1400/4885
US-20260138957-A1 UREA-LINKED 2-AMINOIMIDAZOLE DIMER POTENTIATORS BCR, ATF1, O60361 DGAT1 1457/4885CTSK 2801/4885MAOA 3523/4885
US-12559461-B2 Antibiotic adjuvant compounds MYD88, TLR5, TLR4 DGAT1 2854/4885CTSK 2764/4885MAOA 4119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.