Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6379683 | 0.83 | DGAT1 (0.34) | DGAT1NOS1MAOAMAOBTSHR | |
| SCHEMBL3808765 | 0.82 | CRBN (0.34) | DGAT1MAOAMAOB | |
| SCHEMBL3808762 | 0.82 | CRBN (0.34) | DGAT1MAOAMAOB | |
| SCHEMBL23746404 | 0.82 | DGAT1 (0.42) | DGAT1MAOAMAOB | |
| SCHEMBL3728300 | 0.80 | MAOA (0.36) | DGAT1MAOAMAOBCA2NFKB1 | |
| SCHEMBL601561 | 0.80 | MAOA (0.36) | DGAT1MAOAMAOBCA2NFKB1 | |
| SCHEMBL601562 | 0.80 | MAOA (0.36) | DGAT1MAOAMAOBCA2NFKB1 | |
| SCHEMBL15324528 | 0.79 | APLNR (0.40) | MAOAMAOBLMNA | |
| SCHEMBL3994044 | 0.79 | CA1 (0.35) | DGAT1NOS1CA2LMNACYP3A4 | |
| SCHEMBL320541 | 0.78 | DGAT1 (0.34) | DGAT1NOS1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113943298-A | Synthesis method of guanamine natural product Crambescin A | 中国人民解放军军事科学院防化研究院 | 2022-01-18 | — | — | CN | disclosed |