Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320541 | 0.81 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL17348031 | 0.79 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL17083255 | 0.79 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL8879857 | 0.76 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL8750078 | 0.76 | DGAT1 (0.31) | DGAT1 | |
| SCHEMBL6379683 | 0.74 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL15324947 | 0.74 | DGAT1 (0.30) | DGAT1 | |
| SCHEMBL12317214 | 0.74 | NOS1 (0.43) | DGAT1 | |
| SCHEMBL1136775 | 0.74 | NOS1 (0.43) | DGAT1 | |
| SCHEMBL28705194 | 0.74 | DGAT1 (0.34) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933993-A4 | SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARM INC (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-0933993-A1 | SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS INC. (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1997047194-A1 | SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 1997-12-18 | — | — | WO | disclosed |