Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.32 |
| ▸ | SLC2A3 | P11169 | 2/20 | 0.32 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.32 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3222044 | 0.90 | AR (0.36) | ARSLC2A1SLC2A3SLC2A2TMPRSS4 | |
| SCHEMBL3208889 | 0.88 | KDM4E (0.35) | ARSLC2A1SLC2A3SLC2A4MAPT | |
| SCHEMBL3215598 | 0.88 | ALDH1A1 (0.33) | ARHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL3226967 | 0.85 | AR (0.36) | ARMALT1CISD2TMPRSS4PDK1 | |
| SCHEMBL13456027 | 0.85 | P2RX1 (0.35) | HDAC1CISD2MEN1HTTKMT2A | |
| SCHEMBL1766498 | 0.83 | AR (0.36) | ARHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL3226929 | 0.83 | TAS2R14 (0.38) | MEN1HTTKMT2ATAS2R14MAPT | |
| SCHEMBL3704403 | 0.83 | AR (0.36) | ARSORT1 | |
| SCHEMBL3222031 | 0.82 | KDM4E (0.35) | CISD2MAOAMAOB | |
| SCHEMBL27953249 | 0.81 | PDK1 (0.43) | PDK1PDK2PDK3PDK4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120556-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-09 | — | — | EP | disclosed |
| EP-2120556-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-03-09 | — | — | EP | disclosed |
| US-8389766-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-05 | — | — | US | disclosed |
| US-8389766-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-05 | — | — | US | disclosed |
| US-8389766-B2 | Insecticidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-05 | — | — | US | disclosed |
| US-20100056639-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-03-04 | — | — | US | disclosed |
| US-20100056639-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-03-04 | — | — | US | disclosed |
| US-20100056639-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-03-04 | — | — | US | disclosed |
| EP-2120556-A1 | INSECTICIDAL COMPOUNDS | Syngeta Participations AG (CH) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008074427-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-06-26 | — | — | WO | disclosed |
| WO-2008074427-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056639-A1 | INSECTICIDAL COMPOUNDS | ACHE, CHRM1, NIT2 | AR 1901/4885MALT1 4548/4885HDAC3 485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.