SCHEMBL320559

SCHEMBL320559

CC(=O)Oc1ccc(C=O)cc1OC(C)=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
JUN P05412 1/20 0.57
NFKB1 P19838 1/20 0.57
ALDH1A1 P00352 8/20 0.55
TSHR P16473 2/20 0.55
KDM4E B2RXH2 2/20 0.55
GAA P10253 1/20 0.55
RAB9A P51151 1/20 0.55
MAPT P10636 1/20 0.51
VCP P55072 1/20 0.51
AOX1 Q06278 1/20 0.50
TRIM24 O15164 1/20 0.50
HPGD P15428 1/20 0.50
ALDH5A1 P51649 1/20 0.50
ABAT P80404 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
TRIM33 Q9UPN9 1/20 0.50
ALOX5 P09917 3/20 0.49
FDPS P14324 1/20 0.47
FNTA P49354 1/20 0.47
FNTB P49356 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31190039 1.00 JUN (0.57) JUNNFKB1ALDH1A1TSHRKDM4E
SCHEMBL81717 0.91 ALDH1A1 (0.70) JUNNFKB1ALDH1A1TSHRKDM4E
SCHEMBL29738486 0.91 ALDH1A1 (0.70) JUNNFKB1ALDH1A1TSHRKDM4E
SCHEMBL871742 0.91 ALDH1A1 (0.70) JUNNFKB1ALDH1A1TSHRKDM4E
SCHEMBL1254905 0.87 ALDH1A1 (0.65) JUNNFKB1ALDH1A1KDM4EGAA
SCHEMBL31336541 0.87 ALDH1A1 (0.65) JUNNFKB1ALDH1A1KDM4EGAA
SCHEMBL2390994 0.85 ALDH1A1 (0.47) JUNNFKB1ALDH1A1TSHRKDM4E
SCHEMBL3399371 0.85 ALDH1A1 (0.66) JUNNFKB1ALDH1A1TSHRKDM4E
SCHEMBL17025841 0.85 ALDH1A1 (0.66) JUNNFKB1ALDH1A1TSHRKDM4E
SCHEMBL16320920 0.85 ACHE (0.56) JUNNFKB1ALDH1A1TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0150507-B1 CEPHALOSPORIN DERIVATIVES, PROCESSES FOR PRODUCING THE SAME AND COMPOSITIONS CONTAINING THEM MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1992-08-05 EP claimed
US-4888332-A ANTIBIOTICS MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1989-12-19 US claimed
EP-0142241-B1 DIHYDROXYBENZAMIDE DERIVATIVES HAVING ANTI-INFLAMMATORY ACTIVITY KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-12-02 EP claimed
EP-0150507-A2 Cephalosporin derivatives, processes for producing the same and compositions containing them MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 1985-08-07 EP claimed
JP-8245658-A None JP disclosed
EP-2796442-B1 CAJANINE STRUCTURE ANALOGOUS COMPOUND, PREPARATION METHOD AND USE INST MED BIOTECHNOLOGY CAMS (CN) 2019-03-27 EP disclosed
CN-105030750-B Application of one group of cajanin structurally similar compounds in anti-hepatitis C virus and anti AIDS virus 中国医学科学院医药生物技术研究所 2018-08-28 CN disclosed
CN-103172512-B A group of compounds with similar cajanin structure, preparation method and application 中国医学科学院医药生物技术研究所 2016-08-03 CN disclosed
US-9359298-B2 Cajanine structure analogous compound, preparation method and use INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2016-06-07 US disclosed
CN-105030750-A Application of longistyline structural analogues in prevention of hepatitis C virus and acquired immune deficiency syndrome (AIDS) virus INST MED BIOTECHNOLOGY CAMS 2015-11-11 CN disclosed
CN-104003913-B The preparation method of E-3,4-dihydroxyphenyl vinylic sulfonamides and sulfonates compounds and the application as neuroprotective thereof PEKING UNIVERSITY (CN) 2015-10-07 CN disclosed
CN-102985415-B Xanthenedione derivatives for the treatment of pigmentation and skin aging disorders FABRE PIERRE DERMO COSMETIQUE 2015-07-01 CN disclosed
EP-0046307-B1 NOVEL URACIL DERIVATIVES, PROCESS FOR PREPARING THE SAME AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME Chugai Seiyaku Kabushiki Kaisha (JP) 1984-11-21 EP disclosed
US-4415573-A ANTITUMOR AND ANTICARCINOGENIC AGENTS; REACTING A 1,3-DIOXOLANE AND A URACIL USING AN ACID CATALYST AND SOLVENT CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1983-11-15 US disclosed
US-4415572-A CARDIOTONIC AND INOTROPIC AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1983-11-15 US disclosed
EP-0082501-A1 Beta-lactam compound and a pharmaceutical composition containing the same KYOWA HAKKO KOGYO CO., LTD (JP) 1983-06-29 EP disclosed
EP-0075805-A1 Beta-lactam compound and a pharmaceutical composition containing the same KYOWA HAKKO KOGYO CO., LTD (JP) 1983-04-06 EP disclosed
EP-0046307-A1 Novel uracil derivatives, process for preparing the same and a pharmaceutical composition containing the same Chugai Seiyaku Kabushiki Kaisha (JP) 1982-02-24 EP disclosed
EP-0004727-B1 BLOOD PLATELET AGGREGATION INHIBITORY PYRIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND PROCESSES FOR THEIR MANUFACTURE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-08-12 EP disclosed
EP-0004727-A2 Blood platelet aggregation inhibitory pyridine derivatives, pharmaceutical compositions thereof, and processes for their manufacture IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-10-17 EP disclosed