Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.51 |
| ▸ | ABAT | P80404 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | JUN | P05412 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | VCP | P55072 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3399371 | 0.86 | ALDH1A1 (0.66) | ALDH1A1AOX1KDM4ERAB9APTGS2 | |
| SCHEMBL31190039 | 0.85 | JUN (0.57) | ALDH1A1AOX1KDM4ERAB9ATRIM24 | |
| SCHEMBL320559 | 0.85 | JUN (0.57) | ALDH1A1AOX1KDM4ERAB9ATRIM24 | |
| SCHEMBL29030377 | 0.84 | TRPA1 (0.50) | ALDH1A1AOX1KDM4ERAB9ATTR | |
| SCHEMBL18130100 | 0.83 | IAPP (0.57) | ALDH1A1KDM4ERAB9AHPGDTDP1 | |
| SCHEMBL30488631 | 0.83 | TYR (0.51) | ALDH1A1AOX1HPGDTTRJUN | |
| SCHEMBL18130102 | 0.83 | IAPP (0.57) | ALDH1A1KDM4ERAB9AHPGDTDP1 | |
| SCHEMBL2390994 | 0.82 | ALDH1A1 (0.47) | ALDH1A1AOX1KDM4ERAB9ATRIM24 | |
| SCHEMBL19663397 | 0.81 | ALDH1A1 (0.60) | ALDH1A1AOX1KDM4ERAB9APTGS2 | |
| SCHEMBL19663140 | 0.81 | ALDH1A1 (0.60) | ALDH1A1AOX1KDM4ERAB9APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11654198-B2 | Application of combination of polyethylene glycol and local anesthetic in non-narcotic analgesia | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2023-05-23 | — | — | US | disclosed |
| US-11654198-B2 | Application of combination of polyethylene glycol and local anesthetic in non-narcotic analgesia | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2023-05-23 | — | — | US | disclosed |
| US-11654198-B2 | Application of combination of polyethylene glycol and local anesthetic in non-narcotic analgesia | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2023-05-23 | — | — | US | disclosed |
| EP-3315126-B1 | CONJUGATE OF POLYETHYLENE GLYCOL AND ANESTHETIC, AND PREPARATION METHOD THEREOF | JENKEM TECH CO LTD TIANJIN (CN) | 2022-01-19 | — | — | EP | disclosed |
| EP-3563873-B1 | APPLICATION OF COMBINATION OF POLYETHYLENE GLYCOL AND LOCAL ANESTHETIC IN NON-NARCOTIC ANALGESIA | JENKEM TECH CO LTD TIANJIN (CN) | 2021-07-28 | — | — | EP | disclosed |
| EP-3563873-B1 | APPLICATION OF COMBINATION OF POLYETHYLENE GLYCOL AND LOCAL ANESTHETIC IN NON-NARCOTIC ANALGESIA | JENKEM TECH CO LTD TIANJIN (CN) | 2021-07-28 | — | — | EP | disclosed |
| US-20200147228-A1 | APPLICATION OF COMBINATION OF POLYETHYLENE GLYCOL AND LOCAL ANESTHETIC IN NON-NARCOTIC ANALGESIA | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2020-05-14 | — | — | US | disclosed |
| US-20200147228-A1 | APPLICATION OF COMBINATION OF POLYETHYLENE GLYCOL AND LOCAL ANESTHETIC IN NON-NARCOTIC ANALGESIA | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2020-05-14 | — | — | US | disclosed |
| EP-3563873-A1 | APPLICATION OF COMBINATION OF POLYETHYLENE GLYCOL AND LOCAL ANESTHETIC IN NON-NARCOTIC ANALGESIA | Jenkem Technology Co., Ltd. (Tianjin) (CN) | 2019-11-06 | — | — | EP | disclosed |
| EP-3563873-A1 | APPLICATION OF COMBINATION OF POLYETHYLENE GLYCOL AND LOCAL ANESTHETIC IN NON-NARCOTIC ANALGESIA | Jenkem Technology Co., Ltd. (Tianjin) (CN) | 2019-11-06 | — | — | EP | disclosed |
| US-20180110867-A1 | CONJUGATE OF POLYETHYLENE GLYCOL AND ANESTHETIC, AND PREPARATION METHOD THEREOF | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2018-04-26 | — | — | US | disclosed |
| US-20180110867-A1 | CONJUGATE OF POLYETHYLENE GLYCOL AND ANESTHETIC, AND PREPARATION METHOD THEREOF | JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) | 2018-04-26 | — | — | US | disclosed |
| US-20170340746-A1 | PEGYLATED CARFILZOMIB COMPOUNDS | AMGEN INC. | 2017-11-30 | — | — | US | disclosed |
| US-9126965-B1 | Process for preparing morphine compounds | BROCK UNIVERSITY (CA) | 2015-09-08 | — | — | US | disclosed |
| US-20150239860-A1 | PROCESS FOR PREPARING MORPHINE COMPOUNDS | BROCK UNIVERSITY (CA) | 2015-08-27 | — | — | US | disclosed |
| CN-104671921-A | Preparation method of polyelement composite chelated iron fertilizer | WUHAN SHENGDA SHENNONG BIO ENGINEERING CO LTD | 2015-06-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200147228-A1 | APPLICATION OF COMBINATION OF POLYETHYLENE GLYCOL AND LOCAL ANESTHETIC IN NON-NARCOTIC ANALGESIA | OPRL1, OPRK1, OPRM1 | ALDH1A1 689/4885AOX1 2392/4885KDM4E 1886/4885 |
| US-20170340746-A1 | PEGYLATED CARFILZOMIB COMPOUNDS | MCL1, FCGRT, MAN2B1 | ALDH1A1 2023/4885AOX1 1167/4885KDM4E 519/4885 |
| US-20150239860-A1 | PROCESS FOR PREPARING MORPHINE COMPOUNDS | OPRM1, OPRK1, OPRD1 | ALDH1A1 1077/4885AOX1 1345/4885KDM4E 1980/4885 |
| US-20180110867-A1 | CONJUGATE OF POLYETHYLENE GLYCOL AND ANESTHETIC, AND PREPARATION METHOD THEREOF | OPRL1, OGFR, F12 | ALDH1A1 945/4885AOX1 3148/4885KDM4E 2367/4885 |
| US-11654198-B2 | Application of combination of polyethylene glycol and local anesthetic in non-narcotic analgesia | OPRL1, OPRK1, OPRM1 | ALDH1A1 689/4885AOX1 2392/4885KDM4E 1886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.