Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4100527 | 0.86 | NOTUM (0.49) | NOTUMCASRKCNH2SRCBRAF | |
| SCHEMBL6034578 | 0.82 | TLR8 (0.44) | NOTUMCASRKCNH2SRCBRAF | |
| SCHEMBL5004852 | 0.81 | CTSS (0.44) | NOTUMCASRKCNH2SRCBRAF | |
| SCHEMBL5904591 | 0.76 | PDE2A (0.41) | NOTUMCASRKCNH2SRCBRAF | |
| SCHEMBL6035573 | 0.75 | DDX3X (0.41) | TRPA1 | |
| SCHEMBL6035925 | 0.75 | PTGS2 (0.40) | NOTUMCASRKCNH2SRCBRAF | |
| SCHEMBL5904618 | 0.75 | NOTUM (0.40) | NOTUMCASRKCNH2SRCBRAF | |
| SCHEMBL6157506 | 0.75 | CA12 (0.40) | KCNH2SRCPTGES | |
| SCHEMBL17814158 | 0.74 | CTSS (0.47) | NOTUMCASRKCNH2SRCBRAF | |
| SCHEMBL19807675 | 0.73 | TRPA1 (0.46) | NOTUMCASRKCNH2SRCBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029949-A1 | Activator for Peroxisome Proliferator Activated Receptor | NIPPON CHEMIPHAR CO., LTD. (JP) | 2010-02-04 | — | — | US | disclosed |
| US-20090240058-A1 | Activator for Peroxisome Proliferator-Activating Receptor Delta | NIPPON CHEMIPHAR CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| EP-1916247-A1 | ACTIVATOR OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR | Nippon Chemiphar Co., Ltd. (JP) | 2008-04-30 | — | — | EP | disclosed |
| EP-1854784-A1 | ACTIVATOR FOR PEROXISOME PROLIFERATOR ACTIVATING RECEPTOR | Nippon Chemiphar Co., Ltd. (JP) | 2007-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029949-A1 | Activator for Peroxisome Proliferator Activated Receptor | PPARA, PPARG, PPARD | NOTUM 1392/4885CASR 1970/4885KCNH2 2421/4885 |
| US-20090240058-A1 | Activator for Peroxisome Proliferator-Activating Receptor Delta | PPARG, PPARA, PPARD | NOTUM 2197/4885CASR 1873/4885KCNH2 2226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.