Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21241509 | 0.77 | CES2 (0.31) | NT5E | |
| SCHEMBL31522927 | 0.77 | CA2 (0.38) | NT5ECA2CHKAKDM4E | |
| SCHEMBL16235040 | 0.77 | CA2 (0.38) | NT5ECA2CHKAKDM4E | |
| SCHEMBL3221371 | 0.77 | NT5E (0.30) | NT5E | |
| SCHEMBL3217372 | 0.73 | KDM4E (0.35) | KDM4E | |
| SCHEMBL16064902 | 0.73 | HPGD (0.31) | — | |
| SCHEMBL30374282 | 0.67 | HSP90AA1 (0.42) | NT5ECA2CHKAKDM4E | |
| SCHEMBL21596956 | 0.67 | HSP90AA1 (0.42) | NT5ECA2CHKAKDM4E | |
| SCHEMBL13259534 | 0.65 | NT5E (0.34) | NT5ECA2CHKAKDM4E | |
| SCHEMBL3295796 | 0.64 | TRPV4 (0.48) | NT5ECA2CHKAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109372175-A | A kind of preparation method of mould proof plasterboard | 嘉兴凯蒂市场营销策划有限公司 | 2019-02-22 | — | — | CN | claimed |
| CN-107654011-A | A kind of preparation method of the mould proof plasterboard of modularization plaster tablet suspended ceiling | 江山海维科技有限公司 | 2018-02-02 | — | — | CN | claimed |
| CN-109372175-A | A kind of preparation method of mould proof plasterboard | 嘉兴凯蒂市场营销策划有限公司 | 2019-02-22 | — | — | CN | disclosed |
| CN-109372175-A | A kind of preparation method of mould proof plasterboard | 嘉兴凯蒂市场营销策划有限公司 | 2019-02-22 | — | — | CN | disclosed |
| CN-107762031-A | A kind of modularization plaster tablet suspended ceiling technique | 江山海维科技有限公司 | 2018-03-06 | — | — | CN | disclosed |
| CN-107654011-A | A kind of preparation method of the mould proof plasterboard of modularization plaster tablet suspended ceiling | 江山海维科技有限公司 | 2018-02-02 | — | — | CN | disclosed |
| US-8906921-B2 | 4-alkoxypyridazine derivatives as fast dissociating dopamine 2 receptor antagonists | JANSSEN PHARMACEUTICA NV (BE) | 2014-12-09 | — | — | US | disclosed |
| US-8906921-B2 | 4-alkoxypyridazine derivatives as fast dissociating dopamine 2 receptor antagonists | JANSSEN PHARMACEUTICA NV (BE) | 2014-12-09 | — | — | US | disclosed |
| US-8906921-B2 | 4-alkoxypyridazine derivatives as fast dissociating dopamine 2 receptor antagonists | JANSSEN PHARMACEUTICA NV (BE) | 2014-12-09 | — | — | US | disclosed |
| EP-2148873-B1 | 4-ALKOXYPYRIDAZINE DERIVATIVES AS FAST DISSOCIATING DOPAMINE 2 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2012-08-29 | — | — | EP | disclosed |
| US-20100063058-A1 | 4-ALKOXYPYRIDAZINE DERIVATIVES AS FAST DISSOCIATING DOPAMINE 2 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-03-11 | — | — | US | disclosed |
| US-20100063058-A1 | 4-ALKOXYPYRIDAZINE DERIVATIVES AS FAST DISSOCIATING DOPAMINE 2 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-03-11 | — | — | US | disclosed |
| US-20100063058-A1 | 4-ALKOXYPYRIDAZINE DERIVATIVES AS FAST DISSOCIATING DOPAMINE 2 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2010-03-11 | — | — | US | disclosed |
| EP-2148873-A1 | 4-ALKOXYPYRIDAZINE DERIVATIVES AS FAST DISSOCIATING DOPAMINE 2 RECEPTOR ANTAGONISTS | Janssen Pharmaceutica, N.V. (BE) | 2010-02-03 | — | — | EP | disclosed |
| WO-2008128995-A1 | 4-ALKOXYPYRIDAZINE DERIVATIVES AS FAST DISSOCIATING DOPAMINE 2 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-10-30 | — | — | WO | disclosed |
| WO-2008128995-A1 | 4-ALKOXYPYRIDAZINE DERIVATIVES AS FAST DISSOCIATING DOPAMINE 2 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063058-A1 | 4-ALKOXYPYRIDAZINE DERIVATIVES AS FAST DISSOCIATING DOPAMINE 2 RECEPTOR ANTAGONISTS | DRD2, GRIN2C, GRIN2A | NT5E 1781/4885CA2 3250/4885CHKA 1149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.