Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | GID4 | Q8IVV7 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.43 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
| ▸ | WNT1 | P04628 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3223498 | 1.00 | NPC1 (0.57) | NPC1RAB9ASMYD3USP30GID4 | |
| SCHEMBL13490693 | 0.94 | NPC1 (0.64) | NPC1RAB9ASMYD3USP30GID4 | |
| SCHEMBL13490493 | 0.94 | NPC1 (0.64) | NPC1RAB9ASMYD3USP30GID4 | |
| Trifluoroacetic Acid SCHEMBL3210746 | 0.86 | SMN1; SMN2 (0.47) | RAB9AGID4SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3224147 | 0.85 | NPC1 (0.51) | NPC1RAB9AUSP30GID4SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3220716 | 0.85 | SMN1; SMN2 (0.44) | NPC1RAB9AGID4HTR3ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3215916 | 0.83 | SMN1; SMN2 (0.43) | RAB9AGID4SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3210512 | 0.82 | HTR2B (0.43) | GID4SMN1; SMN2CHEK1 | |
| Trifluoroacetic Acid SCHEMBL3209776 | 0.82 | GID4 (0.40) | USP30GID4SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3218108 | 0.81 | RAB9A (0.52) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | PFIZER INC. | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029615-A1 | BENZIMIDAZOLE DERIVATIVES | ACIN1, HAT1, CCNE1 | NPC1 3250/4885RAB9A 1662/4885SMYD3 223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.