Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 11/20 | 0.50 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3208063 | 1.00 | FOLH1 (0.50) | FOLH1NAALAD2CTSBEGFRCTSD | |
| SCHEMBL3221173 | 0.91 | OPRD1 (0.43) | CTSBOPRM1OPRD1OPRK1 | |
| SCHEMBL3873046 | 0.88 | ALDH1A1 (0.45) | FOLH1CTSBOPRM1OPRD1OPRK1 | |
| SCHEMBL30808873 | 0.87 | ALDH1A1 (0.46) | FOLH1CTSBOPRM1OPRD1OPRK1 | |
| SCHEMBL30844024 | 0.85 | FOLH1 (0.45) | FOLH1CTSBOPRM1OPRD1OPRK1 | |
| SCHEMBL30261857 | 0.84 | FOLH1 (0.47) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL29401142 | 0.84 | EGFR (0.43) | FOLH1EGFR | |
| SCHEMBL29521437 | 0.84 | EGFR (0.43) | FOLH1EGFR | |
| SCHEMBL30881176 | 0.84 | FOLH1 (0.47) | FOLH1CTSBCTSDBACE1 | |
| SCHEMBL8361982 | 0.83 | FOLH1 (0.49) | FOLH1NAALAD2RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962697-B2 | Bioreponsive polymers | INTERFACE BIOLOGICS INC. (CA) | 2015-02-24 | — | — | US | claimed |
| US-8962697-B2 | Bioreponsive polymers | INTERFACE BIOLOGICS INC. (CA) | 2015-02-24 | — | — | US | disclosed |
| US-20100041771-A1 | Bioreponsive Polymers | INTERFACE BIOLOGICS, INC. | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041771-A1 | Bioreponsive Polymers | PEPD, PREP, DNPEP | FOLH1 125/4885NAALAD2 23/4885CTSB 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.