Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7920376 | 0.88 | HTR1A (0.41) | CYP2D6ALDH1A1CYP3A4TSHRCYP2C9 | |
| SCHEMBL3220729 | 0.85 | ALDH1A1 (0.42) | CYP2D6ALDH1A1CYP3A4TSHRCYP2C9 | |
| SCHEMBL3202703 | 0.85 | ALDH1A1 (0.42) | CYP2D6ALDH1A1CYP3A4TSHRCYP2C9 | |
| SCHEMBL3203234 | 0.85 | ALDH1A1 (0.42) | CYP2D6ALDH1A1CYP3A4TSHRCYP2C9 | |
| SCHEMBL730472 | 0.83 | PTGIR (0.46) | CYP2D6ALDH1A1CYP3A4TSHRCYP2C9 | |
| SCHEMBL3207601 | 0.83 | ALDH1A1 (0.40) | CYP2D6ALDH1A1CYP3A4TSHRCYP2C9 | |
| SCHEMBL13487000 | 0.81 | ALDH1A1 (0.42) | CYP2D6ALDH1A1CYP3A4TSHRCYP2C9 | |
| SCHEMBL13487006 | 0.81 | ALDH1A1 (0.42) | CYP2D6ALDH1A1CYP3A4TSHRCYP2C9 | |
| SCHEMBL13487008 | 0.81 | ALDH1A1 (0.42) | CYP2D6ALDH1A1CYP3A4TSHRCYP2C9 | |
| SCHEMBL4224280 | 0.80 | ALDH1A1 (0.41) | CYP2D6ALDH1A1CYP3A4TSHRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | WYETH | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | HTR2C, HTR5A, NPY1R | CYP2D6 554/4885ALDH1A1 1164/4885CYP3A4 298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.